Published in Gene Therapy Weekly, July 14th, 2005
According to a study from the Netherlands, "the vast majority of androgen-dependent prostate tumors progress coward incurable, androgen-independent tumors. The identification of androgen-responsive genes, which are still actively transcribed in the tumors of patients who have undergone androgen ablation, may shed light on the molecular mechanisms underlying this phenomenon."
"To address this question, we chose the Dunning R3327 rat model system, in which the progression from androgen-dependent to -independent tumors is represented by several transplantable prostate-derived...
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