Gene Therapy Weekly

Herpes Vaccine - HSV trafficking and development of gene therapy vectors reviewed

Herpesvirus - Human herpesvirus analyzed, beta-chemokine receptor encoding revealed

Herpesvirus - Studies add new findings to herpesvirus body of knowledge

Human Papillomavirus Vaccine - Adenoviral vectors carrying IL-12 and E7 enhanced immunity to HPV-16

Liposomes - Novel mechanism of hybrid liposomes-induced apoptosis in human tumor cells found

Liver Failure - U.S. NIH SIBR grant awarded for study of stem cell therapeutics in liver disease

Lung Cancer - Researchers find lung cancer may begin in newly isolated lung stem cells

Lysosomal Storage Diseases - Genetically modified cells migrate to brain and treat neurodegeneration

Mergers & Acquisitions - Clinical Data to acquire molecular diagnostics company

Minority Health - Company announces partnership with V-Kardia

Neuroblastic Tumors - Researcher looks at molecular pathology of neuroblastic tumors

Neurodegenerative Disease - Viral vectors used to treat neurodegenerative disorders

Neuroscience - Fluorescent markers provide a way to analyze and manipulate oligodendrocytes

Neuroscience - Peripheral sensory neuron survival studied, role of synucleins clarified

Neuroscience - Survival motor neuron gene deficits leave cells prone to death-causing agents

Oligodeoxynucleotide - Surface binding and internalization drive BCL2 mRNA into K562 cells

Oncology - Researchers' data advance oncology research

Ophthalmology - New findings in ophthalmology described

Organ Transplantation - Dendritic cells expressing indoleamine dioxygenase inhibited T cells

Pain Management - Company announces clinical trial for treatment of critical limb ischemia

Parkinson Disease - Researchers provide details of new studies and findings in the area of Parkinson disease

Personnel - Antibody-focused company appoints Paul Rohricht VP of business development

Personnel - Cancer-focused company elects George Bickerstaff and Garry Willis to board

Personnel - Hematologist Pierre Laneuville, MD, named to cryogenics company advisory board

Pharmaceutical Research - Italian biotech experts visit Temple U to discuss genetic cancer research

Phosphatase - Novel anti-oncogene discovered

Prostate Cancer - Sca-1-enriched prostate-regenerating cells can initiate prostate tumorigenesis

Proteomics - Mass spectrometry products for proteomics research demonstrated at conference

Proteomics - Thyroid transcription factor proteins interact after hepatoma cell gene uptake

Rheumatology - Gene therapy targeting Tie2 activity ameliorates arthritis in animal models

Rheumatology - TIMP-3 governs apoptotic signals in rheumatoid arthritis synovial fibroblasts

Stem Cell Research - Serum free T cell medium for expansion, activation of human T cells introduced

Thyroid Cancer - Combined suicide/cytokine gene therapy kills thyroid carcinoma cells

Transcriptional Repression - Transcriptional repression of p21 studied

Transplant Medicine - Gene silencing prevents PERV infection after pig to human xenotransplantation

Vaccine Delivery - Injection of DNA into skin induces dermatitis via toll-like receptor 9

Vaccine Delivery - Plant and bacterial toxins provide insights on delivery into cells

Vaccine Vector - Intracellular trafficking of adeno-associated viral vectors reviewed

Vaccine Vector - Polyethylenimine vector ability due to avoidance of acidic lysosomes

Vaccine Vectors - Nuclear entry of nonviral vectors reviewed

Vaccine Vectors - Viral vectors produced using recombinase-mediated cassette exchange

Vaccines Vector - Reports add new data to vaccines vector research

Vector Development - Polycations improve lipid emulsion-mediated transfection

Vector Development - Reports advance knowledge in vector development research

Virology - Findings describe new data in virology research

Virology - Hepatitis G virus E2 peptide interactions make vesicles permeable

Virology - Self-complementary adeno-associated virus vectors elucidate recombination