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Cystic Fibrosis

Progress in phase 2 clinical trial of cystic fibrosis drug candidate reported

Published in Gene Therapy Weekly, July 21st, 2005

Inspire Pharmaceuticals, Inc. (ISPH) announced recent developments in its cystic fibrosis (CF) program.

Inspire has completed more than 50% of target enrollment in its ongoing phase 2 safety study, which is a double-blind, randomized comparison of 2 doses of denufosol tetrasodium (INS37217 Respiratory) to placebo in 72 patients with CF at 18 clinical centers across the United States.

This second phase 2 trial is being conducted in order to gain a greater understanding of safety and tolerability of denufosol in a broader population of CF patients, including patients with lower lung function and patients using antibiotics and other therapeutics,...

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