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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . July 28th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Alzheimer Disease - Nerve growth factor gene therapy for Alzheimer disease described

Drug Delivery - Selective stabilized plasmid-lipid particles show longevity

Fibrinogen - Angiopoietin-1 variant discourages neovascular proliferation

Head and Neck Cancer - RNA interference sensitizes oral cancer to chemotherapy

Reconstructive Surgery - Extracorporal shock waves surpass gene therapy for revitalizing skin flaps

Addiction Medicine - New findings in addiction medicine described

Antibacterial Agents - Elafin gene transfer fights pulmonary Staphylococcus aureus infection

Biomedical Engineering - Genomics company launched to develop synthetic approaches to biological energy

Brain Cancer - Hairpin siRNA identifies and shuts down glioma progression factors

Breast Cancer - Clinical significance of transcription factors Snail, Slug, and Twist evaluated

Breast Cancer - New findings in the area of breast cancer described

Oncology - Studies describe new findings in oncology research

Business Update - Gene-based company to list on NASDAQ

Cancer Vaccine - Electroporation is prime/boost strategy for DNA vaccine against cancer

Cardiology - New findings in cardiology described

Cardiovascular Surgery - Research demonstrates potential of TMR Plus gene therapy

Cervical Cancer - Researchers describe findings in cervical cancer studies

Collaborations - Collaboration with Cryptome Pharmaceuticals signed to validate cancer lead

Dermatology - Insulin-like growth factor-I gene transfer speeds wound healing

Dermatology - New research in the area of dermatology detailed

Diabetes Therapy - Transforming growth factor-beta I gene therapy restores beta cell function

Diagnostics - Genetics-focused company contracts with cancer center to develop diagnostic test

Disease Associations - Parkinson disease phenotype examined, protective role of enzymes revealed

Disease Associations - Triple-A syndrome analyzed, novel splice variant of human AAAS characterized

Drug Resistance - Early detection system of drug resistance mutations in myeloid leukemia studied

Endocrinology - Antisense oligonucleotides improve glucose and lipid levels in animal models

Endocrinology - Micro RNAs 15a and 16-1 influence pituitary adenoma growth

Endocytosis - Macrophage mannose receptor studied, role as phagocytic receptor clarified

Enzymology - New findings in enzymology described

Finance - Genetic testing-focused company receives $3.8 million from exercise of warrants

Finance - Medical imaging company reports record performance, expands management team

Gene Transfer - Asialofetuin-labeled liposomes and the AFP promoter enhance transfection

Gene Transfer - New data illuminates research in gene transfer

Genetic Testing - Genetic testing-focused company to supply LabCorp with diagnostic products

Genetics & Genomics - Genetics-focused companies develop mini-lab cartridge to analyze DNA and RNA

Genetics & Genomics - New 15-month policy study of risks and benefits of synthetic genomics set

Glucocorticoid Receptors - Glucocorticoid receptor examined, impaired nuclear translocation identified

Hemophilia Therapy - Self-regulating lentiviral vector expresses human factor IX in vivo

Hepatitis B Therapy - Reports advance knowledge in hepatitis b therapy research

Hepatitis B Vaccine - Non-invasive niosomes offer topical immunization against hepatitis B

Hunter Syndrome - Positive trial results of phase 3 enzyme therapy for Hunter syndrome reported

Information Technology - U.S. FDA licenses analysis software for review of pharmacogenomics submissions

Legal Issues - Company files request to withdraw motion for injunction against Insmed, Celtrix

Leukodystrophy - Galactocerebrosidase expression attenuates globoid cell leukodystrophy

Liver Cancer - Angiostatic therapy hinders hepatocellular carcinoma progression

Neurology - Aprataxin analyzed, effect of disease-associated mutations clarified

Neurology - Huntington disease modeled, neuronal vulnerability revealed

Neurology - Research in neurology provides new insights

Niemann-Pick A Disease - Correction of brain pathology in Niemann-Pick A disease reported

Oncology - Findings describe new data in oncology research

Parkinson Disease - Drug therapy for Parkinson disease available in U.K., European launches planned

Patents - Patent application filed on transrenal DNA technology for infectious diseases

Personnel - Cancer therapeutics development company appoints senior vice president

Personnel - Timothy M. Mayleben elected to bioscience company board of directors

Pharmaceutical Research - Consultancy releases study on pharma industry

Product Licensing - License agreement with Merck entered for use of bacterial cell expression

Prostate Cancer - Regulatory filing process for European approvals of prostate cancer drug begun

Stem Cell Research - Australian officials launch new human embryonic stem cell line, drives network

Stem Cell Research - Long-term survival of blood stem cells reported in cloning and stem cells

Stem Cell Research - Study: Cell nuclear transfer in old animals generates youthful immune cells

Stress - Human lens studied, role of reductases in oxidative stress resistance revealed

Transplant Medicine - New findings in transplant medicine described

Urology - Genetic markers predict clinical outcomes in bladder cancer patients

Vaccine Vector - Two nonviral gene therapy vectors for somatic integration compared

Vector Development - Protein expression using bacterial hemoglobin fusion vector reported

Vector Development - Studies advance knowledge in vector development research

Vector Development - Transduction with viral vectors modulates human dendritic-cell function

Virology - Adenoviral vector binding is toxic to non-targeted tissues

Virology - Virus-encoded inhibitor blocks RNA interference

Virology Vaccine - Use of recombinant viruses as vaccines against viral diseases reviewed

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