Hepatitis B Therapy

Reports advance knowledge in hepatitis b therapy research

Published in Gene Therapy Weekly, July 28th, 2005

Reports from the People's Republic of China, South Africa and United States highlight recent research on hepatitis b therapy.

Study 1: Short hairpin RNA interferes with hepatitis B replication in liver cells.

"Hepatitis B virus (HBV) infection is a worldwide health problem. To determine whether RNA interference (RNAi) could inhibit ongoing HBV replication in 2.2.15 cells, we constructed shRNA- producing vector pU6P based on the mouse U6 RNA promoter and cloned 12 targeted sequences against HBV into the vector, resulting in a series of pU6-siHBV vectors," scientists in the Peoples Republic of China report.

"The recombinant vectors...

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Source: Gene Therapy Weekly (2005-07-28)

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