Gene Therapy Weekly

Gene Transfer - Gene therapy expands the potential of interleukin-13 cytotoxin

Genetics & Genomics - Research study examines gene therapy markets

HIV/AIDS Vaccine - Adenoviral gene delivery for HIV-1 vaccination reviewed

Hematology - RPS 19 depletion blunts erythropoiesis in Diamond-Blackfan anemia models

Hodgkin Lymphoma - bcl-2 expression independent predictor of poor outcome in Hodgkin lymphoma

Lung Cancer - Results of preclinical lung cancer study in mice reported

Marketing - Independent testing to support safety marks for nanoarray system complete

Neuroblastoma - Disruption of cooperation between Ras and MycN promoted growth arrest

Oncogene - microRNA polycistron is potential oncogene

Oncology - Complementary therapies bolster TRAIL-mediated death in breast cancer cells

Patents - ACE System developer strengthens IP estate with four new patents

Patents - Company announces multiple patents covering SVM methods

Patents - Pharmaceutical company issued U.S. drug delivery system patent

Patents - U.K. patents granted covering siRNAs targeting VEGF and HCV

Patents - U.S. patent granted for detecting nucleic acids

Personnel - Claire M. Fraser, PhD, named to National Science Advisory Board for Biosecurity

Personnel - DNA-based diagnostics company names Trevor L. Hawkins to board of directors

Personnel - Gene therapy company adds John Walker to board of directors

Personnel - Mark A. Kahil named VP of investor relations by cell therapies-focused company

Personnel - Pharma company appoints member to board of directors

Prostate Cancer - Interference with HH-GLI signaling inhibits prostate cancer

Prostate Cancer - Membrane type I-matrix metalloproteinase is linked to prostate cancer invasion

Proteomics - Biochemical company introduces new antibody array for protein kinase expression

Proteomics - Method for analyzing protein phosphorylation cell status introduced

Proteomics - Transforming growth factor-beta proteins regulate new vessel formation

RNA Interference - Thioribonucleoside modification enhances short interfering RNA efficacy

Rheumatology - Functional genomic screens reveal new osteoarthritis mediators

Stem Cell Research - Company acquires rights to new stem cells and placenta products

Transplant Medicine - Low dose cyclosporine and interleukin 10 halt lung transplant acute rejection

Tumor Suppressor - Early growth response 1 acted as tumor suppressor via regulation of p53

Tumorigenesis - CD95 has tumor promoting activities

Type 1 Diabetes - Approaches for the cure of type 1 diabetes by cellular and gene therapy

Type 2 Diabetes - Takeda acquires rights to DPP4 inhibitors formerly granted to services provider

Tyrphostin Inhibitors - Tyrphostin inhibitors of cytokine signaling identified

Vaccine Development - Pharma company receives grant to develop thermostable vaccines

Vector Development - Adenovirus CELO vector conveys suicide genes to cancer cells

Vector Development - Cytomegalovirus promoter expression enhanced by exposure to DNA damage agents

Vector Development - DNA shuttling between plasmid vectors resolves preservation concerns

Vector Development - HIV-1-derived lentivirus vector induces megakaryocyte gene expression

Vector Development - Intracarotid delivery of oncolytic HSV vector to brain cancer reported

Vector Development - PEGylated gelatin nanoparticles offer systemic delivery of therapeutic genes

Vector Development - PEGylated helper-dependent adenoviral vectors are highly efficient

Virology - Adenoviral insulating sequences optimize radiation controlled gene expression

Virology - Genetic loci regulate antibody response to adeno-associated virus and factor IX