Gene Therapy Weekly

Gene Research - Tumor stroma hypoxia is a viable target for cancer gene therapy

Gene Transfer - A new antigen-antibody reporting system monitors transgene expression

Gene Transfer - HIV-1 TAT protein transduction domain constructs enhance ganciclovir toxicity

Growth Factor - TGF-beta signaling examined, nature of modulation clarified

HIV/AIDS Vaccine - Current status of gene therapy strategies to treat HIV/AIDS reviewed

HIV/AIDS Vaccine - DNA vaccines expressing different SIV antigens decrease viremia

HIV/AIDS Vaccines - Research in HIV/AIDS vaccines provides new insights

Hemophilia - Gene therapy induces tolerance to factor VIII inhibitors

Hepatitis B Therapy - Lentiviral vectors containing hammerhead ribozymes end hepatitis B activity

Infectious Diseases - Infectious disease institute, DNA technologies developer sign research agreement

Influenza Vaccines - Recent findings in influenza vaccines provide new insights

Leukemia - Rac3 expression cultivates malignant lymphoblast precursors

Liver Cancer - Cantide eradicates tumor growth in hepatocellular carcinoma models

Liver Cancer - Studies describe new findings in liver cancer research

Lung Cancer - DNA methylation disturbances present a new way to target lung malignancies

Lung Carcinoma - Tumor genes with aberrant promoter methylation identified

Melanoma Vaccine - DNA vaccine targets self-antigens expressed in melanoma

Metastatic Melanoma - Human trial of gene-based interleukin-2 with electroporation technology begun

Neuropathy - Diabetic nerve therapy shows "striking" results

Oncology - PIK3CA mutations foster cancer cell growth and invasion

Oncology - Reports add new data to oncology research

Ophthalmology - Antisense constructs abate excess lens epithelial cell proliferation

Ovarian Cancer Therapy - Antisurvivin oligonucleotides generate apoptosis in ovarian cancer cells

Pain Management - U.S. NIH awards $197,000 grant to develop drug candidate for neuropathic pain

Pancreatic Cancer - Activation of RaIA deemed critical for Ras-induced tumorigenesis of human cells

Pancreatic Cancer - KAI1 inhibited pancreatic cancer cell growth

Product Licensing - Licensing agreement signed for drug delivery technology for drug eluting stents

Product Licensing - Life sciences company licenses fundamental RNAi patent estate from Alnylam

Prostate Cancer - Phase 2 clinical trials of OGX-011 for prostate cancer initiated

Proteomics - Antibody array to identify protein kinase expression in cell, extracts launched

Proteomics - Bioscience company offers Protran nitrocellulose membranes for protein research

Proteomics - Maryland companies sign marketing agreement for protein immunodetection products

Renal Disease - Decreased angiotensin II type-1 receptor lowers proteinuria in rats

Reproductive Medicine - Molecular pathways are disrupted in rodent models of testicular dysgenesis

Spinal Cord Injury - Combination therapy leads to partial recovery from spinal cord injury in rats

Stem Cell Research - Biopharm company gets $35 million to create mouse embryonic stem cell library

Tick-Borne Encephalitis - Heterologous gene delivery system developed for tick-borne encephalitis

Transgenics - Peripherin/rds analyzed, consequence of Cys->Ser mutation revealed

Urology - VEGF antisense therapy augments bladder cancer chemotherapy

Vaccine Vector - Mannosylated dendrimer/cyclodextrin conjugates improve gene delivery

Vaccine Vector - Packaging cell line for production of lentiviral vector generated

Vaccines Vector - Researchers provide details of new studies and findings in the area of vaccines vector

Vector Development - Improved inducible lentivirus vectors gain tighter transgene expression

Vector Development - Myocardial gene expression by adeno-associated virus vector achieved

Vector Development - PLGA microspheres with decoy oligonucleotide block nuclear factor-kappa B

Virology - Researchers describe findings in virology studies