Susan Hasty, Publisher
Table of Contents . . . September 1st, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Angiology - Decoy transcription factor prevents abdominal aortic aneurysm formation
Diabetes Therapy - Antisense oligonucleotides improve glucose control in diabetic mice
Myocardial Infarction - Hypoxia-inducible factor 1 alpha augments skeletal myoblast transplantation
Oncology - Interleukin-12 gene transfer and chemotherapy hinders murine tumors
Virology - Transposon-based systems seek insertion sites to improve viral gene delivery
Adenocarcinoma - Transformed bronchioalveolar stem cells give rise to adenocarcinoma
Adenovirus Vector - Capsid modifications enable flexible targeting of adenovirus vectors
Apoptosis - Apoptosis regulated by alternative pre-mRNA splicing
Awards - Society honors five scientists for outstanding work in blood cancer research
Awards - U.S. NIAD grant up to $4.9 million awarded to develop infection biosensor system
Bioinformatics - Web tools facilitate the design and optimization of RNAi constructs
Cancer Vaccines - Researchers detail new studies and findings in the area of cancer vaccines
Brain Cancer - New findings in the area of brain cancer described
Business & Finance - President and CEO Dr. Lawrence Olanoff granted stock option award
Cancer Therapy - CK2 blockade impedes cellular survival
Cancer Vaccines - New findings in the area of cancer vaccines described
Cardiology - Reports add new data to cardiology research
Liver Cancer - Researchers' findings advance liver cancer research
Collaborations - Companies collaborate on DNA vaccine technology
Colon Cancer - Viral vector helps interleukin-12 eliminate murine colon adenocarcinomas
DNA Research - Molecular genealogy foundation to include Singapore families in DNA database
DNA Vaccine - Beta-amino ester polymers facilitate in vivo DNA transfection
DNA Vaccine - Repressor protein immobilized for binding of plasmid DNA
Dermatology - Integrin beta signaling domain effects of deletion defined
Proteomics - New findings in the area of proteomics described
Diabetes Complications - Platelet-derived growth factor gene transfer accelerates diabetic wound healing
Diabetes Therapy - Researchers provide details of new studies and findings in the area of diabetes therapy
Drug Delivery - DMXAA may ease drug and gene delivery by increasing vascular permeability
Drug Delivery - Engineered bio-nanocapsules transport proteins to liver cells
Drug Delivery - Transdermal drug-delivery device company launches human clinical trial
Drug Development - U.S. FDA grants orphan drug status for lysosomal acid lipase product
Proteomics - New research in the area of proteomics detailed
Drug Development - U.S., Japan, Europe have legislation to spur orphan drug production, study says
Enzymology - Anti-uPAR DNAzymes staunch osteosarcoma cell invasion
Enzymology - Small interfering RNA produces gene-specific control in zebrafish embryos
Finance - DNA-focused biopharmaceutical company reports Q2 2005 financial results
Finance - Eligen technology company announces 2005 second-quarter results
Finance - Gene expression-focused biotech company transfers securities to NASDAQ SmallCap
Vector Development - Researchers report details of new studies and findings in the area of vector development
Finance - Genetics-focused biopharmaceutical company reports Q2 2005 financial results
Finance - Personalized health products developer reports Q2 2005 financial results
Finance - Protein therapeutics developer announces proposed common stock offering
Gene Regulation - A WAP-promoter fragment directs gene expression in murine mammary cells
Gene Research - Histone H3 K56 acetylation favors DNA repair
Gene Research - Specific response elements guide p63 activation of targeted genes
Gene Silencing - Short hairpin RNA triggers de novo methylation in human cells
Genetics & Genomics - University of Miami genetics center signs agreement with reagents supplier
Geriatrics - Systematic RNA interference screens nematodes for longevity genes
Glioma - TIMP-3 evokes a number of processes to staunch tumor growth
Grants - Multi-million dollar grant awarded to identify genetic signatures of pathogens
Heart Disease Therapy - Long-term cardiac gene expression achieved using coxsackieviral vector
Human Papillomavirus Vaccines - Reports describe recent advances in human papillomavirus vaccines research
Leukemia - Chronic myeloid leukemia used as model for oncology
Liver Cancer - Adeno-associated virus-mediated TRAIL gene therapy fights cancer metastasis
Liver Cancer - Reports describe recent advances in liver cancer research
Molecular Biology - "Cookbook recipes" would cure disease with nontoxic DNA delivery systems
Myeloma - Atiprimod induced apoptosis in multiple myeloma cells
Obstetrics - In utero gene delivery elucidates placental vascularity in mice
Oncogenes - MET targeted in gene therapy
Pancreatic Cancer - Phase II trial of pancreatic cancer treatment successfully completed
Patents - Gene-focused company announces patent issuance to make adeno-associated virus
Personnel - Biotech company names James Rotherham and Peter Myers to executive positions
Personnel - Cell and gene therapy company adds to scientific advisory board
Personnel - Gene-based pharma company names two directors
Personnel - Michael S. Paul promoted to president, COO by genetics-focused biotech company
Personnel - Nicole Onetto, MD, named senior VP and CMO by protein therapeutics developer
Protein Production - Baculovirus expression optimized for protein production in insect cells
Proteomics - New data illuminates research in proteomics
Receptors - Lung fibrosis analyzed, effect of mutant human epidermal receptor revealed
Renal Cancer - Studies advance knowledge in renal cancer research
Rheumatology - Studies add new findings to rheumatology body of knowledge
Schistosomiasis - Decoy therapy overwhelms parasite-related liver fibrosis
Thyroid Cancer - Value of nm23 as prognosticator of parathyroid neoplasia assessed
Transgenics - Enzyme overexpression analyzed, effect on myelin stability revealed
Urology - Findings describe new data in urology research
Vaccine Vector - Lentiviral vectors appear safe and effective for fetal gene delivery
Vaccine Vector - Transgene expression prolonged in salivary glands after transduction
Vector Development - Conserved regions of tyrosine hydroxylase promoter characterized
Vector Development - Lipid-protamine-DNA complexes deliver antisense c-myc oligonucleotides
Vector Development - Neomycin augments lipid-based oligonucleotide delivery
Vector Development - New data illuminates research in vector development
Vector Development - Targeted polyplexes enhance transfection efficiency
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