Proteomics

New data illuminates research in proteomics

Published in Gene Therapy Weekly, September 1st, 2005

Data on proteomics are outlined in reports from Germany and the United States.

Study 1: Thyroid transcription factor proteins interact after hepatoma cell gene uptake.

"The thyroid transcription factors TTF-1 and Pax8 cooperate in the transcriptional activation of thyroid-specific genes such as thyroglobulin (Tg), thyroperoxidase (TPO), and sodium/iodide symporter (NIS). Dog TTF-1 (dTTF-1) and the human Pax8 (hPax8) gene were transfected in Morris hepatoma (MH3924A) cells to investigate (a) the possible visualization of functional protein-protein interaction and (b) the induction of thyroid-specific gene expression," scientists in Germany...

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Source: Gene Therapy Weekly (2005-09-01)

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