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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . September 8th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Colon Cancer - Genetic screen for candidate tumor suppressors identified REST

Gene Research - Company expands RNAi product line to 50,000 in frozen or plasmid DNA form

Muscular Dystrophy - No small feat: First ever gene therapy success for muscular dystrophy achieved

Parkinson Disease - Continuous delivery of GDNF optimizes neural transplantation therapy

Transplant Medicine - Akt a target for islet transplantation strategies in diabetics

Acute Myeloid Leukemia - Antiangiogenic treatment with endostatin successfully fights AML

Allergy & Immunology - MDP1 appears to be potential adjuvant for CpG DNA-based immune therapies

Alzheimer Disease - New findings in the area of Alzheimer disease detailed

Amyotrophic Lateral Sclerosis - Recent findings in amyotrophic lateral sclerosis described

Alzheimer Disease - New research in the area of Alzheimer disease detailed

Astrocytes - Astrocyte fatty acid incorporation studied, effect of synuclein clarified

Bacterial Infection - PNA exemplifies the great potential of this class of antibacterial agents

Bacterial Sepsis - Antimicrobial peptide WLBU2 has potential application against P. aeruginosa

Beta-Amyloid - Neuroinflammation and dysfunction studied, role of human beta-amyloid defined

Biomedical Engineering - Immunology researchers publish study results on behavior of natural killer cells

Brain Cancer - Combined gene therapy eliminates glioblastoma multiforme in lab studies

Brain Cancer - Researchers investigate tumor environment as gene therapy target

Vaccines Vector - Researchers publish new studies and findings in the area of vaccines vector

Breast Cancer - Migration-stimulating factor linked to tumor progression

Breast Cancer - Researchers suggest subset of breast cancers associated with Chinese patients

Breast Cancer - Study to test warning system and proteomics to detect early breast cancer begun

Business & Finance - Gene-transfer company reports Q2 financial results, updates GENASIS trial

Cancer Vaccines - Research in cancer vaccines provides new insights

Cardiovascular Disease - DNA vaccine with receptor coding plasmids impair cardiac function

Virology - Studies add new findings to virology body of knowledge

Chronic Fatigue Syndrome - Abnormal gene expression patterns identified

Colon Cancer - Genetic screen identified PITX1 as suppressor of RAS activity and tumorigenicity

Cystic Fibrosis - IgE serum levels of limited value for guiding therapy in CF patients with ABPA

DNA Vaccine - Cross-linked small polyethylenimines deliver DNA efficiently to cells

DNA Vaccine - Naked DNA encoding MCP-1 and RANTES protects against renal injury

Diagnostics - Researchers show positive impact of gene marker on DNA stool test

Finance - Gene therapeutics developer reports second quarter 2005 results

Finance - Gene therapeutics developer secures up to $15,000,000 equity line of credit

Finance - Gene-based therapies company reports second quarter 2005 financial results

Finance - Nucleic acids company reports second quarter 2005 results

Gastric Cancer - Cytotoxic effects of pemetrexed in gastric cancer cells discussed

Gene Silencing - Researchers describe findings in gene silencing studies

Genetics & Genomics - Macrogen, Applera Corporation group partner on Korean FDA toxicogenomics study

Genetics & Genomics - Mutation of CYP17 gene identified as potential marker for disease risk in women

Gynecology - Reports advance knowledge in gynecology research

Hemostasis - Researchers find link between low-density lipoprotein receptor and hemostasis

Hepatitis C Virus - Hepatitis C virus NS3 protein's modulating role may facilitate virus life cycle

Hepatitis C Virus - Researchers propose new method for HCV genotyping

Leishmaniasis Vaccine - DNA vaccine protects against Leishmania donovani

Lung Cancer - C-erbB-2 not involved in first steps of lung carcinogenesis

Lung Cancer - Phase 2 clinical trial of non-small cell lung cancer treatment initiated

Lymphoma - Stat3 is a therapeutic target in fight against human lymphoma

Lymphopenia - Researchers investigate role of IL-6 in lymphopoiesis

Malaria Vaccine - Researchers peg five peptides as candidates in designing a malaria vaccine

Melanoma - GSTP1 and MRP1 combine to resist melanoma treatment

Muscular Dystrophy - Researchers' findings advance muscular dystrophy research

Neurology - Studies describe new findings in neurology research

Osteoclast Differentiation - Intracellular reactive oxygen species are signal mediators for differentiation

Pituitary Adenoma - Oligonucleotide array identifies genes linked to pituitary tumor pathogenesis

Professional Education - $1.75 million Genomics Education Matching Fund program for undergrads announced

Rectal Cancer - Chromosome alterations in colorectal cancer observed in Thai patients

Stem Cell Research - NANOG expressed in fetal gonocytes/testicular carcinoma/germ cell tumors

Traumatic Brain Injury - Antagonism of IL-1 improves anatomical and functional outcomes

Urology - New findings in urology described

Vaccine Vector - Interference with IL-1-signaling reduces toxicity of adenovirus vectors

Vaccines Vector - Researchers detail new studies and findings in the area of vaccines vector

Virology - Researchers' work adds to virology body of knowledge

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