Astrocytes
Astrocyte fatty acid incorporation studied, effect of synuclein clarified
Published in Gene Therapy Weekly, September 8th, 2005
"Because alpha-synuclein may function as a fatty acid binding protein, we measured fatty acid incorporation into astrocytes isolated from wild-type and alpha-synuclein gene-ablated mice," wrote P.I. Castagnet and colleagues, University of North Dakota.
"Alpha-synuclein deficiency decreased palmitic acid (16:0) incorporation 31% and arachidonic acid [20:4 (n-6)] incorporation 39%, whereas 22:6 (n-3) incorporation was unaffected. In neutral lipids, fatty acid targeting of 20:4 (n-6) and 22:6 (n-3)...
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Source: Gene Therapy Weekly (2005-09-08)
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