Published in Gene Therapy Weekly, September 8th, 2005
"Antisense oligodeoxynucleotides (ODNs) and their analogs have been successfully utilized to inhibit gene expression and bacterial growth in vitro or in cell culture. In this study, acpP-targeting antisense peptide nucleic acid (PNA) and its peptide conjugate were tested as potential antibacterial agents in two groups of experiments using a mouse model," reported X.X. Tan and associates at Cytogenix in Houston in a recent issue of Antimicrobial Agents and Chemotherapy.
"In the first group,"...
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