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Proteomics

Researchers published expression system for NfdA studies

Published in Gene Therapy Weekly, September 15th, 2005

Researchers in Japan provide an expression system for the study of N-substituted formamide deformylase (NfdA).

According to a study from Japan, "NfdA from Arthrobacter pascens F164 is a novel deformylase involved in the metabolism of isonitriles. The enzyme catalyzes the deformylation of an N-substituted formamide, which is produced from the corresponding isonitrile, to yield the corresponding amine and formate."

H. Fukatsu and associates at the University of Tsukuba in Ibaraki reported, "The nfdA gene from A. pascens F164 was cloned into different types of expression vectors for Escherichia coli and Streptomyces strains. Expression in...

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