Published in Gene Therapy Weekly, September 22nd, 2005
"Unexpended energy is stored as fat in the body and increased rate of fat accretion culminates in obesity. Obesity increases the risks of many diseases several-fold and shortens lifespan. A progressive deficit in the central feedback effects of leptin, a peptide produced by fat cells and hypothalamus, results in increased weight gain and obesity," investigators in the United States report.
"This article summarizes our experimental findings to show that a stable increase in leptin availability in the hypothalamus alone with the aid of leptin...
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