Published in Gene Therapy Weekly, October 6th, 2005
Study 1: According to recently published research from the United States, heat shock protein (Hsp)70 overexpression sequesters apoptosis-inducing factor (AIF) and reduces neonatal hypoxic/ischemic (H/I) brain injury.
"Apoptosis is implicated in neonatal H/I brain injury among various forms of cell death. Here we investigate whether overexpression of Hsp70, an antiapoptotic protein, protects the neonatal brain from H/I injury and the pathways involved in the protection," wrote Y. Matsumori and colleagues, University of California, San Francisco.
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