Gene Therapy Weekly
Susan Hasty, Publisher
Table of Contents . . . November 3rd, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Alzheimer Disease - MEOX2 homeobox gene reduction is linked to neurovascular dysfunction in mice
Biochemical Research - Adenovirus-mediated TPO gene transfer stimulates oval cell proliferation in liver
Infantile Neuronal Ceroid Lipofuscinosis - Intravitreal AAV-mediated gene therapy has direct benefits to the eye
Prostate Cancer - UCLA researchers identify how antibody blocks prostate cancer growth in animal models
Vaccine Development - Positive results of gene-based therapies for HIV, vascular disease published
Assisted Reproduction - Infertility researchers identify one gene's critical role in the human embryo implantation process
Atherosclerosis - CC-chemokine is a potential target for improving vein graft patency
Biomedical Engineering - Researchers offer proof-of-concept for altered nuclear transfer
Brain Cancer - Several genes expressed in human and canine brain tumors suggest common pathogenesis
Breast Cancer - Estrogen receptor-alpha regulates SOCS-3 expression in breast cancer cells
Cancer Research - Cells with duplicate genomes can trigger tumors
Cancer Treatment - Electrical engineer works on personalizing medical treatment
Cardiovascular Research - Measuring C-reactive protein levels can help assess cardiovascular risk
Embryonal Cancer - p27 enhances neural differentiation in pluripotent embryonal carcinoma
Gene Research - Australian broad patent issued covering siRNAs targeting Huntington disease
Genetics & Genomics - Genetic testing company licenses intellectual property from Abbott Labs
Genetics & Genomics - Mitochondrial optimization may be linked to human longevity
Genetics & Genomics - SNCG gene expression by demethylation a critical factor to malignant progress
Geriatrics - "Run-down feeling" with illness may last longer as people age
Glaucoma Vaccine Development - Activation of extracellular signal-regulated kinase protects retinal ganglion cells
Glycogen Storage Disease - rAAV vectors mediate sustained therapeutic levels of correction of skeletal and cardiac muscles
Graves Disease - Animal models show light at end of tunnel in the fight for prevention of Graves disease in humans
Heart Attack - Increasing elastin within myocardial scars shows benefit
Immunology - Recombinant proteins can inhibit NF-kappa B activation
Immunotherapy - The origin of regulatory T cells that "police" and protect the body is revealed
Ischemia - Adenoviral vector shows promise as an investigational tool when looking at neuronal damage
Leukodystrophy - AAV2/5 vector ameliorates CNS disease more efficiently than AAV2
Lung Cancer - Gene therapy may protect normal tissues during radiation retreatment for lung cancer
Lung Cancer - Phosphorylated FADD induces NF-kappa B associated with poor lung adenocarcinomas outcome
Mergers & Acquisitions - Celliance Corp. acquires gene expression technology from Innovata, plc
Molecular Biology - Integration of cell survival signals in PTEN-deficient tumors
Molecular Biology - Key role of signal-transcribing gene during cell cycle discovered
Oncology - Big mitogen-activated protein kinase 1 signals are essential for tumor angiogenesis
Ovarian Cancer - Recruitment for ovarian cancer vaccine clinical trial complete
Prostate Cancer - Prostate cancer in mice blocked by new antiangiogenic agent and radiation
Proteomics - Proteome Systems signs agreement with Prince Henry's Institute for Ovarian Cancer diagnostic test
Pulmonary Medicine - Interleukin-10 gene therapy attenuates pulmonary tissue injury
Rotavirus - Oral immunization of mice with pBsVP6-transgenic alfalfa protects against rotavirus
Stem Cell Research - Mesenchymal stem cells induce apoptosis of activated T cells
Stem Cell Research - SDF-1-CXCR4 axis regulates trafficking of both normal and cancer stem cells
Stem Cell Research - University of Minnesota researchers use human embryonic stem cells to kill cancer cells
Stroke - Stroke treatment a step closer after clinical trial
Toxic Epidermal Necrolysis - Rituximab can trigger toxic epidermal necrolysis in rhesus macaque
Transplantation Medicine - Research indicates TGF-beta1 gene linked with development of regulatory cells
Tumor Suppression - Sequence of tumor suppressor inactivation influences tumorigenicity
Tumor Therapy - Researchers present three-plamid system that eases development of ideal m-CRA
Vaccine Delivery - Detailed guidelines for design of optimal cationic lipids released
Vaccine Vector - Model for intracellular trafficking of adenoviral vectors developed
Vaccines Vector - New findings in vaccines vector described
West Nile Virus - Immunization with Japanese encephalitis vaccine beneficial to those at risk for West Nile
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