Biochemical Research
Adenovirus-mediated TPO gene transfer stimulates oval cell proliferation in liver
Published in Gene Therapy Weekly, November 3rd, 2005
According to M. Ichiba and associates, "Thrombopoietin (TPO) is the growth factor for megakaryocytes and platelets, however, it also acts as a potent regulator of stem cell proliferation. To examine the significance of TPO expression in proliferation of hepatic oval cells, the effect of adenovirus-mediated TPO gene transfer into livers of the Solt-Farber model, which mimics the condition where liver regeneration is impaired, was examined."
The scientists' data...
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Source: Gene Therapy Weekly (2005-11-03)
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