Published in Gene Therapy Weekly, November 3rd, 2005
According to recent research from the United States, "Here we develop an integrative computational framework to model biophysical processes involved in viral gene delivery. The model combines reaction-diffusion-advection equations that describe intracellular trafficking with kinetic equations that describe transcription and translation of the exogenous DNA. It relates molecular-level trafficking events to whole-cell distribution of viruses."
"The approach makes use of the current understanding of cellular processes and data from single-particle single-cell...
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