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Vaccines Vector

Researchers' work adds to vaccines vector body of knowledge

Published in Gene Therapy Weekly, November 24th, 2005

Vaccines vector data are the focus of recent research from the United States and Canada.

Study 1: Scientists report the results of an analysis of adeno-associated virus vector integration sites in normal human cells in a recent issue of the Journal of Virology.

"The integration sites of viral vectors used in human gene therapy can have important consequences for safety and efficacy. However, an extensive evaluation of adeno-associated virus (AAV) vector integration sites has not been completed, despite the ongoing use of AAV vectors in clinical trials. Here we have used a shuttle vector system to isolate and analyze 977 unique AAV...

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