Published in Gene Therapy Weekly, November 24th, 2005
Study 1: Surface properties, more than size, limits convective distribution of virus-sized particles and viruses in the central nervous system (CNS).
According to recent research from the United States, "Achieving distribution of gene-carrying vectors is a major barrier to the clinical application of gene therapy. Because of the blood-brain barrier, the distribution of genetic vectors to the central nervous system (CNS) is even more challenging than delivery to other tissues. Direct intraparenchymal microinfusion, a minimally invasive technique, uses bulk flow...
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Source: Gene Therapy Weekly (2005-11-24)
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