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Vaccines Vector

Researchers' data advance vaccines vector research

Published in Gene Therapy Weekly, November 24th, 2005

Data on vaccines vector are outlined in reports from the United States and France.

Study 1: Surface properties, more than size, limits convective distribution of virus-sized particles and viruses in the central nervous system (CNS).

According to recent research from the United States, "Achieving distribution of gene-carrying vectors is a major barrier to the clinical application of gene therapy. Because of the blood-brain barrier, the distribution of genetic vectors to the central nervous system (CNS) is even more challenging than delivery to other tissues. Direct intraparenchymal microinfusion, a minimally invasive technique, uses bulk flow...

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