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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . December 1st, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Gene Research - Vascular endothelial growth factor gene change enhances safety of gene therapy

Gene Research - sFlt-1 gene therapy halts pathological neovascularization in animal eyes

Macular Degeneration - RS1 gene therapy aids X-linked juvenile retinoschisis murine models

Peripheral Vascular Disease - Gene therapy promotes arteriogenic and angiogenic responses in ischemic limbs

Antibacterial Agents - REP8839 antibacterial activity is due to inhibition of a methionyl-tRNA synthetase

Atherogenesis - Human paraoxonase-3 can be cloned and highly expressed

Atherosclerosis - Researchers' findings advance atherosclerosis research

Awards - Cincinnati scientist honored for discoveries of genetic mutations implicated in cardiac disease

Breast Cancer - Differential gene expression occurs after chromosome transfer into breast cancer cells

Breast Cancer - Dual cancer-specific targeting cures primary and distant breast carcinomas

Cancer Therapy - Carcinoma cells with impaired cyclooxygenase-2 are radiation sensitive

Cancer Therapy - Chromosome breakpoints in neuroblastoma at sub-kilobase resolution revealed

Cancer Therapy - Gene delivery may be an effective therapy for hepatoma

Cancer Therapy - Human telomerase reverse transcriptase gene may be therapeutic in bladder cancer

Cancer Therapy - Suicide gene expression may be useful in deletion of tumorigenesis

Clinical Trials - Clinical trial to examine prophylaxis treatment for hereditary angioedema

Colon Cancer - Ig-4-1BB ligand-IL-12 gene combination eradicates hepatic colon carcinoma

Coronary Artery Bypass - Researchers find gene variants predict heart tissue damage after cardiac surgery

DNA Vaccine - Electroporation-mediated DNA vaccination potentiates immune responses

DNA Vaccine - Method to deliver plasmid DNA into cell nucleus developed

DNA Vaccine - Survival gene Bcl-xl potentiates DNA-raised antitumor immunity

Diabetes Pathology - Unexpected function for a key regulator of blood glucose levels is reported

Disease Associations - Astrogliosis in epilepsy leads to overexpression of adenosine kinase

Drug Development - Fibroblast growth factor-1 mutants may be capable of treating human disease

Enzymology - Telomerase catalytic subunit sequences are needed for transcriptional activity

Epidemiology - Inter-species genetic movement may blur the epidemiology of endemic streptococcal diseases

Gene Delivery - Nanoparticle delivery system guides design of gene delivery to liver

Gene Research - International consortium completes catalog of human genetic variation

Gene Research - Production of B. thuringiensis insecticidal proteins genetically enhanced

Gene Therapy - Fractalkine gene therapy for neuroblastoma is more effective with interleukin

Genetics & Genomics - Chromatin signaling during skeletal myogenesis presents targets for gene expression

Genetics & Genomics - Mammalian species can be identified using genosensors

Genetics & Genomics - Nonsense termination can be suppressed using antisense agents

Genetics & Genomics - Subtle gene expression changes detected in T cells during anti-tumor response

Hematology - Researchers' data advance hematology research

Hepatitis B Therapy - Hepatitis B virus surface antigen expression is inhibited by RNA

Hepatitis C Virus - Hepatitis C virus inhibits intracellular interferon alpha expression in hepatic cells

Hepatitis C Virus - Hepatitis C virus mutations confer resistance to RNA-dependent RNA polymerase inhibitor

Hepatitis E Virus - Hepatitis E virus capsid protein constituents allow self-assembly into empty virus-like particles

Immunotherapy - Clinical trials are underway to enhance immune systems of breast and colorectal cancer patients

Infectious Diseases - HIV-1 Rev interacts with tumor virus RNA and upregulates gene expression

Infectious Diseases - Novel genes active in the memory response to Brucella infection

Neuroscience - Immature Ucn antisense RNA is expressed naturally in the rat brain

Neuroscience - MIT researcher presents new view of how the cortex forms

Parasitology - Long-term suppression of cathepsin B levels retards schistosome growth

Personnel - Academic researchers named to senior posts to lead U.K.-based research programs

Pulmonology - Growth of alveoli and lung capillaries charted in animal model

RNA Research - Research on RNA splicing may have implications for the study of memory, learning, and cognition

Reconstructive Surgery - Vascular endothelial growth factor gene transfer kindles vascularization in ischemic surgical flaps

Regeneration - Amelogenin stimulates bone sialoprotein expression

Schizophrenia - Independent laboratory licenses first DNA test for response to schizophrenia treatment

Tumor Suppressors - Deleted in Liver Cancer suppresses cell proliferation in hepatocellular carcinoma

Vaccines Vector - Studies add new findings to vaccines vector body of knowledge

Virology - Mitochondrially targeted enzymes rescue null fibroblasts

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