Cancer Therapy
Chromosome breakpoints in neuroblastoma at sub-kilobase resolution revealed
Published in Gene Therapy Weekly, December 1st, 2005
"Understanding the genes and genetic pathways targeted by recurrent chromosomal imbalances in malignancy, along with the molecular mechanisms that generate the imbalances, are important problems in cancer biology. In this report, we demonstrate that oaCGH analysis can routinely map chromosomal imbalance breakpoints at exon-level resolution, including imbalances that are single copy number genomic alterations," wrote R.R. Selzer and colleagues, NimbleGen Systems Inc.
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Source: Gene Therapy Weekly (2005-12-01)
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