Published in Gene Therapy Weekly, December 1st, 2005
"ADK is considered to be the key regulator of the brain's endogenous anticonvulsant, adenosine. In adult brain, ADK is primarily expressed in a subpopulation of astrocytes and striking upregulation of ADK in these cells has been associated with astrogliosis after kainic acid-induced status epilepticus (KASE) in the kainic acid mouse model of temporal lobe epilepsy."
D.E. Fedele and colleagues, University of Zurich, wrote" "To investigate the causal relationship between KASE-induced astrogliosis,...
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