Susan Hasty, Publisher
Table of Contents . . . December 8th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Atherosclerosis - Studies show apo A-I Milano gene transfer cuts atherosclerotic plaque
Cancer Therapy - Gene therapy with sonoporation is feasible for hepatocellular carcinoma
Cancer Therapy - Somatostatin receptor transfection inhibits Panc-1 cell proliferation
Genetics & Genomics - A thermoresponsive copolymer vector is suitable for gene transfection
Pulmonary Medicine - Bronchopulmonary dysplasia models thrived after receiving proangiogenic gene therapy
Alzheimer Disease - 3-D structure of Alzheimer disease filament solved by researchers
Apoptosis - Caspase-9 is regulated in glucocorticoid-induced apoptosis
Apoptosis - Rho GDP dissociation inhibitor protects cancer cells against apoptosis
Apoptosis - TAK1 blockage sensitizes cells to apoptosis and affects tumor necrosis target genes
Breast Cancer - Hyaluronan synthase suppression inhibits breast cancer tumorigenesis
Breast Cancer - Immunity to breast cancer achieved using transfected fibroblasts
Breast Cancer - Protein marker reported to be associated with positive outcomes in invasive breast cancer
Business & Finance - Biopharmaceutical company reports net loss of $10.1 million in third quarter
Cancer Gene Therapy - Chronic gene delivery of interferon-inducible protein suppresses tumor growth
Cancer Gene Therapy - Gene therapy may purge leukemia cells from hematopoietic progenitor cells
Cancer Therapy - Advances evident in glioma molecular analysis and characterization
Cancer Therapy - Gas-filled microparticles and sonoporation are effective against tumors
Cancer Therapy - Gene therapy with histone deacetylase inhibitor enhances transgene expression
Cancer Therapy - HSV-based gene therapy enhances mitomycin efficacy in bladder cell carcinoma
Cancer Therapy - Inactivation of p53 sensitized astrocytic glioma cells to cancer drugs
Cancer Therapy - Melanoma-specific expression achieved in first-generation adenoviral vectors
Cancer Therapy - RNAi-mediated knockdown restores imatinib sensitivity in resistant CML cell lines
Cancer Therapy - Telomerase is synergistically down regulated in squamous cell carcinoma cells
Cancer Therapy - Virus-mediated metalloproteinase inhibition does not alter antitumor efficacy
Cancer Therapy - p53 protein transduction therapy facilitates glioma cells' anti-cancer effect
Cancer Vaccines - Oncolytic vaccinia viruses show promise in treatment of cancer
Cardiology - Renin-angiotensin system antagonists counteract myocardial angiogenesis in the normal heart
Cervical Cancer - New gene silencing for cervical cancer proposed by researchers
Collaborations - Researchers introduce molecular therapy for heart failure
DNA Research - Antisense knockdown of isoquinoline binding protein achieved in C6 glioma cell line
DNA Research - Genomic imprinting recapitulated in the human beta-globin locus
DNA Research - Sp1 and Sp3 regulate basal transcription of the human CYP2F1 gene
DNA Research - Systemic antisense oligodeoxynucleotide administration targets tumor growth
DNA Research - Triple helix-forming oligonucleotides conjugate to topoisomerase II inhibitors
Diagnostics - Test developed for detection of major human respiratory viruses
Disease Associations - A human mineral dust-induced gene is a cell growth regulating gene associated with lung cancer
Disease Associations - Altered axonal architecture slows amyotrophic lateral sclerosis
Gene Research - Recombinant adeno-associated virus vector expression can be enhanced in the lung
Gene Research - VP22 does not significantly enhance enzyme prodrug cancer gene therapy
Genetics & Genomics - Expert panel makes recommendations for DNA-based identification after mass disasters
Genetics & Genomics - Gene thought to influence perception gene was important in human evolution, scientists say
Genetics & Genomics - MC4R gene tissue specific expression requires one kb of the 5' flanking sequence
Genetics & Genomics - Mutations in the Braf gene predict sensitivity to novel class of cancer drugs
Genetics & Genomics - Natural antisense mRNAs inhibit hyaluronan biosynthesis and cell proliferation
Genetics & Genomics - Pituitary adenoma differential gene expression is detected by array analysis
Genetics & Genomics - System reported for inducible gene expression in retinal ganglion cells
Growth Hormone Therapy - Animal models for growth hormone gene therapy are reviewed
HIV/AIDS Vaccine - TRIM5 alpharh expression restricts HIV-1 infection in CD34+-cell-derived macrophages
Hepatitis B Virus - Stable inhibition of hepatitis B virus proteins is achieved by viral vector RNA
Hepatitis E Virus - Novel human hepatitis E virus (HEV) may be seroprevalent in Korea
Leukemia Vaccine - Lentivirus conjugation to paramagnetic particles allows infection of leukemia cells
Lung Cancer - Aberrant methylation of FBN2 detected in human non-small cell lung cancer
Melanoma - Combined effects evident in melanoma drug resistance
Nanotechnology - Monoclonal antibody-coated nanotubes may offer cost-effective way to identify cancer cells
Nanotechnology - Nanodelivery systems target primary and metastatic tumors
Nanotechnology - Scientists create a new way to study T cell signaling
Neuroscience - A transcriptional regulatory strategy may achieve neovascularization after cerebral ischemia
Neuroscience - Number, ratio of serotonin receptors found to influence brain's response to fear and stress
Neuroscience - siRNA-mediated gene knockdown is a useful strategy to study gene function
Parkinson Disease - A new drug target is identified for fighting Parkinson disease
Parkinson Disease - Parkinson disease, ALS, and stroke symptoms may be preventable, according to new studies
Patents - U.S. patent granted for system to measure normal range of gene expression
Stem Cell Differentiation - Inhibition of AF116909 gene expression enhances the differentiation of neural stem cells
Stem Cell Research - IRES technology license expanded for gene expression in mice, stem cells
Tuberculosis Vaccine - Advances in adenovirus- and poxvirus-vectored TB vaccines are reviewed
Vector Development - HSV-1-derived vectors for gene transfer and gene therapy are reviewed
Virology - Epstein-Barr virus LMP1 initiates cell growth and apoptosis inhibition in nasopharyngeal carcinoma
Virology - Herpes simplex fusions produce poor intercellular transport proliferation
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