DNA Research

Double-stranded RNA induces sequence-specific antiviral silencing

Published in Gene Therapy Weekly, December 15th, 2005

According to a study from the United States, double-stranded RNA (dsRNA) induces sequence-specific antiviral silencing.

"dsRNA is a common by-product of viral infections and a potent inducer of innate antiviral immune responses in vertebrates. In the marine shrimp Litopenaeus vannamei, innate antiviral immunity is also induced by dsRNA in a sequence-independent manner."

"In this study," wrote J. Robalino and colleagues, Hollings Marine Laboratory, "the hypothesis that dsRNA can evoke not only innate antiviral immunity but also a sequence-specific antiviral response in shrimp was tested."

"It was found that viral...

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Source: Gene Therapy Weekly (2005-12-15)

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