Cancer Therapy
IL-17 enhances angiogenic activity and growth of non-small cell lung cancer
Published in Gene Therapy Weekly, December 22nd, 2005
"In this study," wrote M. Numasaki and colleagues, Tohoku University, "we examined the biological action of IL-17 on human NSCLC."
"Although IL-17 had no direct effect on the in vitro growth rate of NSCLC, IL-17 selectively augmented the secretion of an array of angiogenic CXC chemokines, including CXCL1, CXCL5, CXCL6, and CXCL8 but not angiostatic chemokines, by three different NSCLC lines."
"Endothelial cell chemotactic activity (as a measure of net...
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Source: Gene Therapy Weekly (2005-12-22)
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