Published in Gene Therapy Weekly, December 22nd, 2005
"Allograft rejection is induced by graft tissue infiltration of alloreactive T cells that are activated mainly in secondary lymphoid organs of the host."
"DOCK2 plays a critical role in lymphocyte homing and immunological synapse formation by regulating the actin cytoskeleton, yet its role in the in vivo immune response remains unknown," wrote H.S. Jiang and colleagues, Kyushu University.
"We show here that DOCK2 deficiency enables long-term survival of cardiac allografts across...
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