Gastroenterology
Hepatocyte growth factor promotes mucosal repair in inflammatory bowel disease
Published in Gene Therapy Weekly, December 29th, 2005
Investigators in Japan wrote, "the repair of intestinal mucosal injuries is a tightly regulated process involving epithelial restitution, cell proliferation and maturation, and the dedifferentiation of epithelial cells. Deeper injuries also require additional repair mechanisms, including inflammatory processes, angiogenesis, and extracellular-matrix deposition."
"Once intestinal mucosal injury occurs, numerous growth factors and cytokines, including HGF, keratinocyte growth factor, endothelial growth factor, epidermal growth factor, transforming growth...
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Source: Gene Therapy Weekly (2005-12-29)
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