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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . January 12th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Colon Cancer - Immunity induced by injection of dendritic cells expressing interleukin-15

Diabetes Vaccine - Glucagon-like peptide-1 plasmid is constructed for type 2 diabetes therapy

Gene Therapy - Retroviral suicide gene therapy achieves long-term survival in glioma

T Cells - Effector function mediated by gene-engineered T cells

Vector Development - Liposomal characteristics influence therapeutic response in acute wounds

Adeno-Associated Viral Vector - Efficient gene expression is produced by trans-splicing adeno-associated viral vectors

Adenovirus - Nonhuman adenovirus alters human memory T cells

Alzheimer Disease - Ubiquilin regulates presenilin proteolysis and modulates secretase components

Antisense Technology - Antisense oligonucleotide induces apoptosis and enhances chemosensitivity in prostate cancer cells

Antisense Technology - LIX antisense oligonucleotide therapy reduces murine colitis

Apoptosis - Apoptosis induced by folate receptor-mediated delivery of recombinant caspase

Cancer Therapy - Recent findings in Cancer Therapy provide new insights

Apoptosis - L-Ala-induced changes protect pancreatic cells from cytokine-induced apoptosis

Apoptosis - Low- and high-molecular-weight poly(L-lysine)-DNA complexes initiate apoptosis differently

Apoptosis - Normal cells produce and release an apoptosis-inducing cytokine

Autoregulation - G-protein-coupled receptor kinase contains an accessorial autoregulatory domain

Breast Cancer - Novel group of genes regulates drug susceptibility in breast cancer cells

Cancer Gene Therapy - Combinatorial antiangiogenic gene therapy regresses tumors in glioblastoma

Cancer Gene Therapy - E2F-1 gene therapy up-regulates PKR and inhibits growth of leiomyosarcoma

Cancer Gene Therapy - PKR-induced mammalian cell death tested in an antisense cellular screening assay

Cancer Gene Therapy - Tropism expanded in a human adenoviral vector with a chimeric fiber

Cancer Therapy - Affymax, partner present preclinical data for novel angiogenesis inhibitors

Cancer Therapy - Extracellular matrix adherence linked to suppression of peritoneal implantation

Cancer Therapy - Findings in Cancer Therapy provide new insights

Cancer Therapy - Glioma cell growth inhibited by siRNA targeting of growth factor

Cancer Therapy - Human acute lymphoblastic leukemia cells produce human pregnancy hormone hCG

Cancer Therapy - Use of agarose capsules chemotherapeutically targets tumors

Cancer Vaccine - Herpes simplex virus type-1 amplicons linked to vaccine generation in lymphoblastic leukemia

Cancer Vaccine - Study identified amino acids of Sindbis virus protein involved in targeting tumor metastases

Colon Cancer - Galectin-3 modulates MUC2 mucin expression in human colon cancer cells

Cytomegalovirus - Adeno-associated virus type-2 infection reduces the grafted cell survival

DNA Damage - Jun activation domain-binding protein required for mitotic checkpoint activation

DNA Vaccines - Researchers describe findings in DNA Vaccines studies

Diabetes Vaccine - DNA vaccine ameliorates type 1 diabetes in NOD mice

Drug Development - Plasminogen kringle 5 deletion mutant may control pathological angiogenesis

Esophageal Cancer - Basic fibroblast growth factor risk for esophageal cancer is ameliorated

Finance - Cell therapy report added to Research & Markets' offerings

Gastroenterology - Macrophage migration inhibitory factor supports intestinal tumorigenesis

Gastroenterology - Monocyte chemoattractant protein-1 boosts angiogenesis in gastric cancers

Gene Expression - Gene expression cascades influence valproic acid-induced skeletal malformations

Gene Research - Coronary microvascular endothelial cell growth regulates gene expression

Gene Research - siRNAs improve RNA interference efficiency

Gene Therapy - Conference discussed scientific and regulatory issues of gene therapy bio-safety

Gene Therapy - Detection time determined for the efficiency of siRNA-induced gene silencing

Gene Therapy - Genetic approach permits access to serotonin neurons

Gene Therapy - Ribozyme-mediated targeted replacement specifically regresses human cancer cells

Genetics & Genomics - Collaboration receives $3 million grant to obtain DNA sequence of Phytophthora capsici genome

Genetics & Genomics - GATA-1 and Oct-1 are required for expression of hemoglobin-stabilizing gene

HIV/AIDS Genomics - Viral infectivity factor binds cooperatively and specifically to HIV-1 RNA

Hepatitis B Therapy - Researchers provide details of new studies and findings in the area of Hepatitis B Therapy

Hepatitis B Virus - A hydrophobic domain is essential for fusion of duck HBV at the late endosome

Hepatitis C Virus Therapy - Anti-hepatitis C virus effects of interferon and ribavirin detected

Hormones - Ecdysone receptor function is influenced by ultraspiracle/retinoid X receptor

Imaging - Herpes viral thymidine kinase-1 reporter gene expression imaged

Imaging - Imaging of prostate cancer achieved using adenovirus-expressed symporter

Imaging - PET imaging detects mesenchymal stem cell targeting of microscopic tumors

Imaging - Transplanted living functional cells noninvasively imaged

Insulin Resistance - Conjugated linoleic acid promotes human adipocyte insulin resistance

Lactation - Weaning induces NOS-2 expression in the lactating mammary gland

Microencapsulation - Micro- and nanospheres used for DNA encapsulation are characterized

Obesity Therapy - Hypothalamic pro-opiomelanocortin gene delivery ameliorates obesity

Ovarian Cancer - Intracellular topotecan may be mediated by gene products in ovarian cancer cells

Ovarian Cancer - KiSS1 suppresses metastasis in human ovarian cancer

Pancreatic Cancer - Extracellular matrix stimulates reactive oxygen species production in pancreatic cancer cells

Prostate Cancer - Melastatine member is involved in channel activation in prostate cancer

Prostate Cancer - Phorbol ester-induced apoptosis in prostate cancer cells detailed

Proteomics - Presenilin homologues function non-redundantly in proteolysis

Proteomics - Vascular endothelial growth factor receptors show interactions within endothelial cells

Pulmonary Medicine - Findings describe new data in Pulmonary Medicine research

Rheumatoid Arthritis Therapy - Adeno-associated virus type 5 enhances gene transfer to arthritic joints

Smooth Muscles - Smoothelin-A functions in intestinal smooth muscle contractility

Squamous Carcinoma - Immune response induced by liposomal transfection of squamous carcinoma cells

Stroke - Gene therapy enhances angiogenesis in brains with cerebral hypoperfusion

T Cells - T cell depletion enhances dendritic cell cytotoxic T lymphocyte response

Transporters - Methylation regulates glucose transporter promoter

Tumor Therapy - Iodobenzylguanidine and topotecan combination effectively treats tumors

Tumor Therapy - Tumor eradication enhanced by interleukin electrotransfer

Vaccine Development - Downstream processing of viral vectors and vaccines is changing

Vaccine Vector - Akt/protein kinase B activation contributes to NF-kappa B-dependent CXCL10 expression

Vector Development - Review examines cellular factors influencing Semliki Forest Virus vector biology

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