Apoptosis
Normal cells produce and release an apoptosis-inducing cytokine
Published in Gene Therapy Weekly, January 12th, 2006
"Melanoma differentiation associated gene-7 (mda-7) was cloned using subtraction hybridization from terminally differentiated human melanoma cells. Based on structural and functional properties, mda-7 is now recognized as interleukin-24 (IL-24), a new member of the expanding IL-10 gene family," wrote Z.Z. Su and colleagues, Columbia University.
"Unique properties of mda-7/IL-24 include its ability to selectively induce growth suppression, apoptosis and radiosensitization in diverse human cancer...
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Source: Gene Therapy Weekly (2006-01-12)
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