Gastroenterology
Monocyte chemoattractant protein-1 boosts angiogenesis in gastric cancers
Published in Gene Therapy Weekly, January 12th, 2006
"MCP-1 is a chemokine that has various roles in tumor development and progression. We previously reported that expression of MCP-1 is associated with macrophage infiltration and tumor vessel density in human gastric carcinomas," researchers in Japan report.
"The present study was undertaken to obtain direct evidence that MCP-1 participates in recruitment of macrophages and induction of angiogenesis. We did transfection experiments to analyze the role of MCP-1 in tumorigenicity and angiogenesis in gastric carcinoma in nude mice," wrote T. Kuroda and colleagues,...
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Source: Gene Therapy Weekly (2006-01-12)
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