Tumor Therapy
Tumor eradication enhanced by interleukin electrotransfer
Published in Gene Therapy Weekly, January 12th, 2006
"Injection of DNA via electric pulses into targeted tissues is referred to as electrotransfer. Intratumoral electrotransfer of the IL12 gene is more effective than intramuscular electrotransfer of the same gene in the eradication of established tumors," wrote S.L. Li and colleagues, Louisiana State University.
"To understand the underlying immunological mechanisms, T cell infiltration, CTL activity, inhibition of angiogenesis, and transgene expression were analyzed using...
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Source: Gene Therapy Weekly (2006-01-12)
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