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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . January 19th, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

Cardiology - New technique may allow stents deliver gene therapy to patients with heart disease

DNA Research - Human RISC couples microRNA biogenesis and posttranscriptional gene silencing

Genetics & Genomics - A novel genomic DNA expression system utilizes a human artificial chromosome vector

Genetics & Genomics - Aromatase genetic variation may contribute to estrogen-dependent disease

Herpes Simplex Virus - Efficacy of oncolytic HSV-1 vectors are improved by multiple transgenes

Angiology - Beta2 -adrenergic receptor overexpression regulates angiogenesis in response to ischemia

Antisense Technology - RNA ortholog of the Prader-Willi/Angelman syndrome is dynamically regulated

Apoptosis - Jurkat T cells can be sensitized to necrosis during cell death

Cancer Gene Therapy - ASH1 gene is a specific therapeutic target for lung cancers

Cancer Gene Therapy - Akt blocks breast cancer cell motility and invasion

Cancer Gene Therapy - Expression of migration stimulating factor is uniquely controlled

Cancer Gene Therapy - Integration of the Sleeping Beauty transposon replicates liver tumor development

Cancer Inhibition - 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside inhibited cancer cells

Cancer Therapy - Adeno-associated virus transduction efficiency improved in human cancer cells

Cancer Therapy - Impaired retinoic acid signal leads to receptor silencing and resistance

Cancer Therapy - Investigational therapy enhances breast cancer treatments, preclinical studies show

Cancer Therapy - SIRT1 is a target for killing epithelial cancer cells

Cancer Therapy - Studies describe new findings in Cancer Therapy research

Cancer Vaccines - Recent studies add new data to Cancer Vaccines research

Cell Differentiation - Key role for integrin in glandular morphogenesis and differentiation revealed

Cervical Cancer - Aberrant cell cycle regulation may aid in progression and development of cervical cancer

DNA Research - Optimized TRAP assay remains nonspecific for telomerase inhibitors

Genetics & Genomics - Gene expression can be altered in an anaplastic thyroid carcinoma cell line

Genetics & Genomics - Oct4 pseudogenes are transcribed in cancers

Genetics & Genomics - Pluripotency homeobox gene NANOG expressed in germ cell tumors

Genomics - Researchers beginning to identify genes that are modified in some diseases

Hearing Disorders - Cu/Zn superoxide dismutase contributes to age-related hearing loss

Heart Failure - Heart failure modeled in a transgenic mouse model using inducible Galphaq

Inflammation - p53 regulates gene expression in chronic inflammatory stress

Leukemia - Allogeneic transplant overcame poor prognosis of chronic lymphocytic leukemia

Macrophages - Induced interleukin-beta expression can be inhibited in macrophages

Marketing - RNAi market predicted to be worth $850 million by 2010, $1.2 billion by 2015, report says

Mergers & Acquisitions - Gene therapy technology acquired by Genzyme

Mergers & Acquisitions - Nucleic acids supplier acquires GenBase and west coast oligo production capability

Metastasis - Melanoma differentiation associated gene is a positive regulator of metastasis

Neuroscience - D-Ser-regulated transcript dsr-2 can be cloned from rat cerebral neocortex

Obesity - Beta2-adrenoceptor gene haplotype may have protective effect against obesity in women

Oncology - Myeloma cell gene regulation produces osteopontin and angiogenesis

Oral Cancer - Transfection efficiency of cationic liposomes is influenced by cell proliferation

Ovarian Cancer - Ets-1 up-regulated by hydrogen peroxide

Pancreatic Cancer - Survivin-specific small inhibitory RNA inhibited growth of pancreatic cancer

Personnel - Joseph "Skip" Klein, III joins RNA-focused pharmaceutical company board

Reconstructive Surgery - New findings in the area of Reconstructive Surgery detailed

Stroke - Growth factor augments bone marrow stromal cell transplantation after cerebral infarction in rats

Varicella-Zoster Virus - A cosmid-based system inserts genes into the simian varicella virus genome

Virology - Mannose-binding lectin genotype BB may be associated with susceptibility to HTLV

Virology - New findings in virology described

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