Published in Gene Therapy Weekly, January 19th, 2006
According to a study from Italy, "Beta2 ARs are widely expressed, although their physiological relevance in many tissues is not yet fully understood. In vascular endothelial cells, they regulate NO release and vessel tone."
"Here we provide novel evidence that beta2 ARs can regulate neoangiogenesis in response to chronic ischemia. We used in vivo adenoviral-mediated gene transfer of the human beta2 AR to the endothelium of the rat femoral artery and increased beta2 AR signaling...
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