Cancer Gene Therapy
ASH1 gene is a specific therapeutic target for lung cancers
Published in Gene Therapy Weekly, January 19th, 2006
"Lung cancers with neuroendocrine features are usually aggressive, although the underlying molecular mechanisms largely remain to be determined," wrote H. Osada and colleagues, Aichi Cancer Center.
"The basic helix-loop-helix protein, achaete-scute complex-like 1/achaete-scute homologue 1 (ASHI), is expressed in normal fetal pulmonary neuroendocrine cells and lung cancers with neuroendocrine elements and is suggested to be involved in lung carcinogenesis."
"In the present study,"...
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Source: Gene Therapy Weekly (2006-01-19)
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