Susan Hasty, Publisher
Table of Contents . . . January 26th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Antisense Technology - Cell surface conjugates can be antisense blocked in Entamoeba histolytica
Epstein-Barr Virus - Proliferation of EBV-positive Burkitt lymphoma cells is inhibited by RNA interference
Gene Therapy - Antagomirs silence microRNAs
Gene Therapy - Recombinant antibodies deliver peptides for deletion of antigen-specific CD4+8+ thymocytes
Infectious Diseases - Induced expression of melittin suppresses Chlamydia and Mycoplasma infections
Alzheimer Disease - New findings in the area of Alzheimer Disease described
Antisense Technology - Nuclear receptor 5a2 functions in skeletal muscle organization
Apoptosis - Inhibited nuclear translocation overcomes apoptosis signaling defects in B-cell malignancies
Apoptosis - Inhibition of apoptosis triggers hepatocarcinogenesis
Apoptosis - Researchers describe findings in apoptosis studies
Biomedical Engineering - Transfected stromal cells improve the fate of healing bone grafts
Blood Cells - A Ser protease in blood cells regulates the melanization reaction in Drosophila
Breast Cancer - Breast cancer resistance protein may not be primarily involved in multiple myeloma
Breast Cancer - Faults in newly discovered breast stem cells may lead to tumors
Breast Cancer - New findings in Breast Cancer described
Breast Cancer - RNA interference in breast cancer cells alters differentiation and proliferation
Cancer Cells - Three-dimensional culture of melanoma cells impairs their immunorecognition
Cancer Research - Advances reported in development of oncolytic viruses for cancer treatment
Cancer Research - Results of in vitro bone marrow cancer cell study show gene technology effective
Cancer Research - U.S. DOD awards $1.5 million in research funding to Nebraska cancer center
Cancer Therapy - Antisense/radiation therapy effectively treats nasopharyngeal cancer
Cancer Therapy - Cytochrome modulation triggers apoptosis in tumor cells
Cancer Therapy - Findings describe new data in Cancer Therapy research
Cancer Therapy - Loss of the hSNF5 gene inactivates replicative senescence in rhabdoid tumors
Cancer Therapy - Melanoma differentiation-associated gene has diverse antitumor properties
Carcinogenesis - UV-induced mutant p53 and skin tumors analyzed by mutation spectra and induction kinetics
Cell Therapy - Autologous cells from fat tissue revive new vessel growth in ischemic limbs
Clear Cell Sarcoma - Up-regulation of neural markers detected in clear cell sarcoma of the kidney
Colon Cancer - Reports add new data to Colon Cancer research
DNA Research - Acidity and structure of nucleosome assembly protein mediate assembly of core particles
DNA Research - Loss of a splicing factor induces cell cycle arrest and apoptosis
DNA Research - Silencing Cenp-F prevents chromosome alignment and activates the spindle checkpoint
DNA Research - Werner protein protects nonproliferating cells from oxidative DNA damage
DNA Vaccines - Studies advance knowledge in DNA Vaccines research
Developmental Biology - Ocular lens development is regulated by Smad-interacting protein 1 involving Foxe3 activation
Developmental Biology - Slow muscle regulates the pattern of trunk neural crest migration in zebrafish
Diabetes Complications - Microangiopathy may influence normocytic normochromic anemia
Drug Development - A new RNA aptamer targeting alphavbeta3 integrin hinders endothelial cell growth and survival
Endocrinology - Phosphoinositide signaling controls beta-cell secretion in insulin exocytosis
Finance - Cancer-focused drug delivery company to raise about $15.8 million through equity funding
Gene Expression - A novel survival-related gene controls apoptosis and tumorigenesis
Gene Research - Small RNA regulates endothelial nitric oxide synthase
Gene Therapy - Effect of epidermal growth factor receptor inhibitors on gliomas studied
Helicobacter Pylori - H. pylori conjugative transfer is mediated by relaxase and traG-like proteins
Hematology - Sickle cell disease corrected in human models using stem cell-based gene therapy
Hepatitis C Virus - Reports add new data to Hepatitis C Virus research
Hyperbilirubinemia - Delivery of naked plasmid DNA into muscle corrects hyperbilirubinemia
Hypertension - Relaxin increases cardiac output and reduces systemic arterial load
Immunoglobulins - MRE11/RAD50 cleaves DNA in an immunoglobulin gene diversification pathway
Infectious Diseases - Legionella acquires type IV secretion substrates via horizontal gene transfer
Leukemogenesis - MEK kinase 1 essential for Bcr-Abl-induced STAT3 and self-renewal activity in ESCs
Malaria - Clip domain Ser proteases function in the malaria vector Anopheles gambiae
Marketing - Exaeris commences formal operations
Melanoma - O-6-benzylguanine and BCNU did not improve outcome of melanoma
Mergers & Acquisitions - Extensive gene therapy assets acquired
Muscular Dystrophy - Gene therapy for muscular dystrophy fixes frail muscle cells in animal model, study finds
Neuroblastoma - Gene described that halts spread of aggressive childhood cancer
Neuroscience - Hippocampal plasticity-related proteins are regulated strain-dependently
Neuroscience - Neuronal differentiation is unaffected by the reduction of neuropathy target esterase
Neuroscience - Serotonin transporter gene polymorphisms influence cognitive abilities
Personnel - Bioactive peptides developer appoints Richard M. Cohen to its board of directors
Physiology - Decreased intestinal glucose transport revealed in absence of a kinase isoform
Physiology - Interleukin receptor antagonist purified
Product Licensing - Biopharmaceutical company licenses anti-sickling agent from Virginia Commonwealth
Prostate Cancer - Increased Hsp27 facilitates androgen-independent progression in prostate cancer
Prostate Cancer - Recent studies add new data to Prostate Cancer research
Proteomics - A large volume of oxygen can be dissolved in recombinant albumin clusters
Proteomics - Adiponectin represses gluconeogenesis independent of insulin in hepatocytes
Proteomics - Researchers' data advance proteomics research
Ribosomes - Assembly of the 30S ribosomal subunit utilizes different conformations
Smooth Muscle Cells - TRPC6 channels mediate Ca2+ signal generation in A7r5 smooth muscle cells
Stem Cell Research - Data show hair follicle stem cells rival embryonic stem cells in regenerative potential
Stroke - Recombinant factor VIIa is potentially useful for intracerebral hemorrhage
Tumors - Cytotoxic T cell functions are directly targeted during tumor evasion of immune surveillance
Ulcerative Colitis - New drug application filed with U.S. FDA on mesalamine treatment for ulcerative colitis
Vaccine Delivery - Amine groups in the structure of polymeric transfectant affect DNA delivery
Vaccine Delivery - Thiol-modified gelatin nanoparticles for intracellular DNA delivery have been developed
Vaccine Development - Turning off molecular "brake" boosts immune response in mouse model of HIV
Vaccine Vector - Membrane-based technology reduces purification time for viral vectors
Varicella-Zoster Virus - Small plaque varicella-zoster virus mutants are defective in viral gene expression
Vector Development - Intelligent polymers show promise as nonviral vectors
Vector Development - Researchers' findings advance Vector Development research
Vector Development - Review examines obstacles and advances in intracellular trafficking of retroviral vectors
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