Developmental Biology

Slow muscle regulates the pattern of trunk neural crest migration in zebrafish

Published in Gene Therapy Weekly, January 26th, 2006

Recently published research from the United States has reported that slow muscle regulates the pattern of trunk neural crest migration in zebrafish.

"In avians and mice, trunk neural crest migration is restricted to the anterior half of each somite. Sclerotome has been shown to play an essential role in this restriction; the potential role of other somite components in specifying neural crest migration is currently unclear."

"By contrast," wrote Y. Honjo and colleagues, University of Oregon, "in zebrafish trunk neural crest, migration on the medial pathway is restricted to the middle of the medial surface of each somite. Sclerotome comprises only a...

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Source: Gene Therapy Weekly (2006-01-26)

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