Hypertension

Relaxin increases cardiac output and reduces systemic arterial load

Published in Gene Therapy Weekly, January 26th, 2006

According to a recent study from the United States, relaxin increases cardiac output (CO) and reduces systemic arterial load in hypertensive rats.

"Chronic administration of recombinant human relaxin (rhRLX) to conscious, normotensive rats (male and female) increases CO and global arterial compliance (AC(g)) and reduces systemic vascular resistance (SVR) with no change in mean arterial pressure (MAP). Effects (magnitude and temporal pattern) of relaxin on systemic hemodynamics and arterial properties in hypertensive animal models are not known."

"Accordingly," wrote D.O. Debrah and colleagues, Magee Women's Research Institute, "the major goal of the...

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Source: Gene Therapy Weekly (2006-01-26)

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