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Gene Therapy Weekly

Susan Hasty, Publisher

Table of Contents . . . February 2nd, 2006

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Gene Therapy Weekly | Other Publications

DNA Research - Cationic liposomes permit naked plasmid DNA uptake in human macrophages

Gene Therapy - Cell-permeable HBV-like particles allow efficient gene transfer into hepatocytes

Gene Therapy - Engineered T lymphocytes resist cytokine withdrawal-induced apoptosis

Hepatitis B Virus - Hepatitis B virus replication is inhibited by various RNAi constructs

Addiction Medicine - Gene transfer of GLT-1 attenuates morphine-induced place preference in rats

Antisense Technology - Antisense treatment influences E-cadherin in human gastric carcinoma cells

Apoptosis - Notch signaling induces growth arrest and apoptosis in B-cell malignancies

Atherosclerosis - Fas ligand gene transfer increases vulnerability of atherosclerosis

Cancer Gene Therapy - 5-fluorouracil and gemcitabine enhance gene therapy in pancreatic cancer

Cancer Gene Therapy - Adeno-associated virus serotypes 1 to 5 mediate tumor cell directed gene transfer

Cancer Gene Therapy - Adenoviral-mediated gene therapy elevates activated partial thromboplastin time in prostate cancer

Cancer Gene Therapy - Gene transfer of growth factor receptor suppresses pulmonary metastasis

Cancer Gene Therapy - Novel oncolytic adenovirus targets tumor-associated polo-like kinase 1

Cancer Gene Therapy - Oral adeno-associated virus-sTRAIL gene therapy suppresses hepatocellular carcinoma

Cancer Therapy - Growth factor receptor signaling promotes non-small cell lung cancer tumor survival

Chemotherapy - MDR1 locus displays epigenetic changes in response to chemotherapeutic drugs

Clinical Trials - Results of second phase 1 trial for GERD therapy, plans for RLS treatment program reported

Collaborations - Collaboration inked for trial for the treatment of critical limb ischemia with VEGF-2

DNA Research - Reporter gene dilution does not alter polyethylenimine transfection efficiency

Developmental Biology - Hematopoietic stem cells can be identified early in zebrafish embryo development

Developmental Biology - Maternal Xenopus negatively regulates nodal-related gene expression

Developmental Biology - POPK-1/Sad-1 kinase is required for translocation in the ascidian embryo

Drug Resistance - Trypanosma resistance to berenil is associated with upregulation of TeDR40

Gene Research - A genome-wide RNA interference screen detects Hh signaling pathway components

Gene Therapy - Adult neural stem cells are refractory to adenovirus-mediated gene transfer

Hepatitis B Virus - CpG oligodeoxynucleotide-activated mononuclear cells display anti-HBV effects

Hepatitis D Virus - Hepatitis B virus replication is inhibited by hammerhead ribozymes

Hepatocellular Cancer - Conditionally replicative adenovirus vectors facilitate enhanced hepatocellular carcinoma oncolysis

Imaging - Researchers report details of new studies and findings in the area of imaging

Insulin Therapy - Brain plays key role in controlling blood sugar levels

Leukemia - PARP-1 down-modulation in leukemia cells restores transcriptional responsiveness

Lung Cancer - Differential CXCR4 expression influences cancer cell metastatic potential

Matrix Metalloproteinase - Ligand interactions and substrate specificities overlap in MMP-9 and -2

Melanoma - Vascular endothelial growth factor loop promotes melanoma cell invasiveness

Muscular Dystrophy - Aggregation of expansion mutant of PABPN1 in HeLa cells is reduced by HSP70

Neuroscience - A segment of the Mecp2 promoter is sufficient to drive expression in neurons

Neuroscience - EphA/ephrin-A signaling controls corticothalamic and thalamocortical axon targeting

Parkinson Disease - Gene delivery of GDNF protects nerves in rat model of Parkinson disease

Prostate Cancer - Hydrogen peroxide boosts proliferation and migration of prostate cancer cells

Prostate Cancer Vaccine - Report presents map of PSMA epitopes recognized by antibodies induced by gene-based vaccines

Pulmonary Fibrosis - Pulmonary fibrosis is adenosine dependent in adenosine deaminase-deficient mice

Quality Assurance - Transdermal drug delivery company achieves ISO quality management system certification

Rheumatoid Arthritis - Fiber modifications enhance gene delivery to arthritis synovium

SARS - Antibody against SARS-coronavirus nucleocapsid protein cross-reacts with IL-11

Schistosomiasis - New research in the area of schistosomiasis detailed

Stem Cell Research - Homeobox gene loss impairs proliferation of hematopoietic stem cells

Stem Cell Research - Targeting cancer stem cells may inhibit tumor progression and disease recurrence

Stem Cell Research - Two breast stem cell types may be origin for ER alpha-positive and -negative breast tumors

Stem Cell Research - Wnt/beta-catenin signaling functions in human embryonic stem cells

Tobacco Use - Nrf2 is activated by aqueous extracts of cigarette smoke

Vaccine Development - Oligopeptide from HIV-1 Vpr improves gene expression in resting macrophages

Vaccine Vectors - Adenovirus infection promotes LPS-induced TNF production and sensitizes to lethal shock

Vaccines Vector - Recent studies add new data to vaccines vector research

Vector Development - Artificial chromosome vector provides effective transgene expression

Vector Development - Reports advance knowledge in vector development research

Virology - A viral gene promoter is subject to circadian control

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