Developmental Biology
Lhx2 mediates the activity of Six3 in zebrafish forebrain growth
Published in Gene Therapy Weekly, February 9th, 2006
"The telencephalon shows the greatest degree of size variation in the vertebrate brain. Understanding the genetic cascade that regulates telencephalon growth is crucial to our understanding of how evolution of the normal human brain has supported such a variation in size."
"Here," wrote H. Ando and colleagues, RIKEN, "we present a simple and quick approach to analyze this cascade that combines caged-mRNA technology and the use of antisense morpholino oligonucleotides in zebrafish embryos."
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Source: Gene Therapy Weekly (2006-02-09)
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