HIV/AIDS Vaccine
Plasmid DNA and adenovirus vector with type 35 fiber protects against HIV
Published in Gene Therapy Weekly, February 9th, 2006
According to recent research from Japan and the United States, "Immunization involving a DNA vaccine prime followed by an adenovirus type 5 (Ad5) boost elicited a protective immune response against SHIV challenge in monkeys. However, the hepatocellular tropism of Ad5 limits the safety of this viral vector. This study examines the safety and immunogenicity of a replication-defective chimeric Ad5 vector with the Ad35 fiber (Ad5/35) in BALB/c mice and rhesus monkeys."
"This novel Ad5/35 vector showed minimal...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2006-02-09)
More Articles from Gene Therapy Weekly
- Antisense Technology
Antisense knockdown of cyclin E does not affect the midblastula transition - Gene Therapy
Adenovirus genome insertion sites utilize splicing machinery for therapeutic gene expression - Gene Therapy
Erythropoietin gene transfer reduces risk of germ cell loss caused by cryptorchidism - Gene Therapy
Norepinephrine transporter contributes to PET of gene therapy - Gene Therapy
Sea urchin sns chromatin insulator characterized in erythroid cells - Acute Respiratory Distress Syndrome
Study reveals new player in sepsis-associated condition - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
