Gene Therapy Weekly

Gonadotropins - Gonadotropin-releasing hormone induces actin cytoskeleton remodeling and affects cell migration

Hepatitis B Virus - HBV genotype and promoter mutations affect HBV e antigen expression

Hepatitis C Virus - Researchers' data advance hepatitis C virus research

Hepatocellular Cancer - Protein kinase C alpha expression is regulated in human hepatocellular carcinoma

Herpesvirus - New findings in herpesvirus described

Huntington Disease - Dysregulation mediates aberrant caspase-1 activation in Huntington disease

Hypoxia - HIF up-regulation in hypoxia is required for pulmonary artery fibroblast responses

Infectious Diseases -  Toxoplasma gondii from immunocompromised patients are frequently type I

Ischemia - Modified troponin I protein protects against major cardiovascular damage

Leukemia - Leukemia xenografts are inhibited by adenovirus-mediated tissue inhibitor

Lung Cancer - Human lung cancer tumors are suppressed by a nuclear export mediator

Lung Cancer - Iodide sensitizes non-small cell lung cancer cells to ionizing radiation

Lung Cancer - Novel EGFR gene mutation could improve lung cancer patients' response to therapy

Medulloblastoma - Tumor suppressors collaborate with Patched to suppress medulloblastoma formation

Multiple Sclerosis - Responsiveness to interferon in multiple sclerosis is genetically varied

Neurodegenerative Diseases - Determinants of exon 7 splicing identified in spinal muscular atrophy genes

Neuroscience - Thalamocortical neuron receptors are a molecular target for hypnotics

Ovarian Cancer - Ovarian tumor xenografts are imaged and treated using sodium iodide symporter-mediated radioiodide

Patents - U.S. patent application filed for synDNA vaccines and other therapeutic compounds

Patents - U.S. patent covering synthesis and manufacture of RNA granted

Physiology - Microtubules have differential roles in megakaryocyte proplatelet formation

Prostate Cancer - A replicating adenovirus is useful for the treatment of prostate cancer

Prostate Cancer - Adenovirus-mediated expression sensitizes prostate carcinoma cells to apoptosis

Prostate Cancer - Adoptive splenocyte transfer is therapeutic in a mouse prostate cancer model

Proteomics - Cytosolic delivery of a p16-peptide oligopeptide occurs through membrane transduction

Renal Cell Carcinoma - Manipulation of B7-H1 is a viable therapeutic option in patients with RCC

Retinitis Pigmentosa - Retinitis pigmentosa Noerg-1 mutation of rhodopsin characterized and cloned

Stem Cell Research - ATR/Chk1 pathway inhibition induces a p38-dependent S-phase delay in ESCs

Stem Cell Research - Lentiviral expression of Pdx1- and Pdx1-VP16 reprograms liver-stem WB cells

Stroke - Research add new data to stroke body of knowledge

Transplant Medicine - Adenoviral bcl-2 transfer improves post-transplantation survival and early graft function

Vaccine Delivery - Inorganic materials for gene-based nano-medicine delivery are focus of review

Vaccine Delivery - Review describes recent advances in lipid molecular design

Vaccine Delivery - Review examines chromosome engineering for delivery of therapeutic genes

Vaccine Delivery - Review examines nanotechnology for drug and gene therapy

Vaccine Delivery - Study examined delivery of ODN into saphenous veins and adjunct effect of ultrasound

Vaccine Vector - Adenovirus vector-incorporating antibody achieves targeted gene delivery

Vector Development - Antigen-presenting cells in CNS are targeted using hematopoietic stem cells

Vector Development - Findings advance knowledge in vector development research

Vector Development - Researchers develop all-in-one gene delivery system to open new treatment avenues

Vector Development - Trophic activity of rabies equine infectious anemia viral vector mediates neuron gene transfer