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Ovarian Cancer

Ovarian tumor xenografts are imaged and treated using sodium iodide symporter-mediated radioiodide

Published in Gene Therapy Weekly, February 16th, 2006

Recent research from the United States has described sodium iodide symporter (NIS)-mediated radioiodide imaging and therapy of ovarian tumor xenografts in mice.

"Ovarian cancer represents the fifth leading cause of cancer death among women in the United States, with 416,000 deaths expected this year. This study was carried out to investigate the potential of NIS-mediated radioiodide therapy as a novel approach for ovarian cancer treatment," wrote R.M. Dwyer and colleagues, Department of Endocrinology & Internal Medicine.

"Radioiodide is routinely and effectively used for the treatment of benign and malignant thyroid disease as a result of native...

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