Susan Hasty, Publisher
Table of Contents . . . March 2nd, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Genetics - PKCalpha expression is regulated by Elk-1 and MZF-1 in hepatocellular carcinoma
Gene Therapy - BACE1 deletion rescues temporal memory deficits in Alzheimer mouse models
Gene Therapy - Direct targeting of modified tumor cells to Fc gamma RI triggers cytotoxicity
Gene Therapy - Inhibitor of Apoptosis Protein 2 regulates innate immune signaling in Drosophila
Gene Therapy - STAT3 activation is differentially regulated in squamous cell carcinomas
Addiction Medicine - New findings in addiction medicine described
Alzheimer Disease - Genomic regulation in microglia perturbs genes relevant to Alzheimer disease
Anti-Inflammatories - COX mechanisms play a role in maintaining pain hypersensitivity
Apoptosis - Arsenic trioxide is a novel human neutrophil pro-apoptotic agent
Apoptosis - Data advance knowledge in apoptosis research
Apoptosis - Phorbol ester-induced apoptosis in prostate cancer cells involves protein kinase C delta
Apoptosis - Suppression of PKCalpha may contribute to hepatic apoptosis during sepsis
Apoptosis - p53 deficiency rescues apoptosis and differentiation of multiple cell types
Atherosclerosis - Local vascular endothelial growth factor gene transfer may not prevent arterial restenosis
Biomedical Engineering - Injectable nanofibers allow controlled protein delivery to myocardium
Bone Development - Bone morphogenetic protein-15 helps regulate oocyte maturation
Bone Development - The peripheral cannabinoid receptor CB2 regulates bone mass
Brain Cancer - Molecularly targeted therapy for pediatric brain tumors discussed
Breast Cancer - PIK3Ca mutations correlate with gene expression and drug sensitivity
Cancer Gene Therapy - Spirulina platensis phycocyanin antitumoral activities are affected by CD59
Cancer Gene Therapy - AIM2 suppresses human breast cancer cell proliferation and mammary tumor growth
Cancer Gene Therapy - Adenovirus vector is more infective for esophageal and oral carcinoma cells
Cancer Gene Therapy - p27(KIP1) prolongs cell cycle and induces apoptosis in gastric cancer cells
Cancer Gene Therapy - p53 cDNA sequence mutations are introduced by a retroviral vector
Cancer Research - Genetics research may hold key to destroying cancer cells
Cancer Research - Protein suppresses growth of head and neck tumors
Cancer Therapy - Alemtuzumab induces caspase-independent cell death in lymphocytic leukemia cells
Chemotherapy - Findings describe new data in chemotherapy research
Clinical Trials - Enrollment opened in phase 2 trial of DNA vaccine against cytomegalovirus
Cystic Fibrosis - Cationic lipid mediated gene transfer is inhibitory in CF tracheal gland cells
Cytokines - Splenocyte cytokines are induced by heat shock proteins and concanavalin A
DNA Research - Transcriptional activation is stimulated by bidirectional RNA polymerase II elongation
Depression - Gene therapy used to prevent depression in mice
Developmental Biology - Crescent modulates Wnt signaling in early Xenopus embryogenesis
Developmental Biology - Rac1 activation by RhoG regulates cell migration
Diet & Nutrition - Beef tallow increases linoleic acid potency in reduction of mammary tumor metastasis
Disease Associations - Natural killer cells are immunoselected that lack stress-inducible ULBP
Doxorubicin - Doxoform suspected as a prodrug for doxazolidine
Finance - TEDCO awards grant for a smallpox DNA vaccine delivery project
Gastric Cancer - Low intra-tumor variability revealed in gastric cancer
Gastric Cancer - Polo-like kinase 1 depletion inhibits mitosis and apoptosis of gastric cancer cells
Genetics & Genomics - RNAi Consortium member introduces lentiviral shRNA gene family set for gene silencing
Genetics & Genomics - SNAI1, functioning as E-cadherin repressor, is implicated in gastric cancer
Genetics & Genomics - Scientists force viruses to evolve as better delivery vehicles for gene therapy
Gynecology - Calcyclin-binding protein may help regulate apoptosis during early pregnancy
HIV/AIDS Genetics - HIV-1 RNA binding protein interacts with Dicer and functions in RNA silencing
HIV/AIDS Mutations - HIV-1 subdomain insertions alter polymerase fidelity and mutation frequencies
Head & Neck Cancer - p63 implicated as survival factor for tumor cells of head and neck cancers
Hepatitis Vaccines - HBV CpG-optimized protein and DNA vaccines perform poorly in chimpanzees
Imaging - Imaging reveals effects of bronchodilator and airway clearance treatment in cystic fibrosis
Infectious Diseases - Haemophilus influenzae adherence upregulates ICAM-1 expression
Inflammatory Bowel Disease - Inflammatory bowel disease is treatable using NF-kappaB decoy oligonucleotides
Lung Cancer - Tumor cell-stromal fibroblast interaction revealed in model of human small-cell lung cancer
Natural Killer Cells - NK cell-mediated cytotoxicity involves three sequential membrane impairment steps
Neuroscience - Caspase-1 activates caspase-6 in human apoptotic neurons
Neuroscience - Recent findings illuminate research in neuroscience
Neuroscience - Research in neuroscience provides new insights
Ovarian Cancer - Research add new data to ovarian cancer body of knowledge
Ovarian Cancer - Suppression of natural killer cell response mediated by the ovarian tumor marker CA125
Patents - Transdermal science company serves patent infringement notice for insulin delivery system
Pharmaceutical Research - Drug delivery company, Donaldson launch jointly developed nanofiber cell culture product
Prodrugs - Tumor necrosis factor prodrug restores membrane TNF-like activity
Product Licensing - Hepatitis C virus license agreement signed with Chiron
Reproductive Biology - Recombinant human lutropin alfa is not useful in late stimulation assisted reproduction cycles
Rett Syndrome - Brain derived neurotrophic factor alleviates symptoms of Rett syndrome in mouse model
Rheumatoid Arthritis - Pristane induces MHC class II-restricted, arthritogenic T cells
Stem Cell Research - Functional mammary gland generated from a single stem cell
T Cells - CD8+ and CD4+ T-cell tolerances can be broken
T Cells - TNF receptor type 2 co-stimulates antigen-driven T cell responses in vivo
Thrombocytopenia - Recombinant factor VIIa can control bleeding caused by thrombocytopenia
Transplant Medicine - Studies describe new findings in transplant medicine research
Vector Development - Dendrimers in gene delivery are focus of review
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