Gene Therapy

Inhibitor of Apoptosis Protein 2 regulates innate immune signaling in Drosophila

Published in Gene Therapy Weekly, March 2nd, 2006

According to a study from Germany, an RNA interference screen identifies Inhibitor of Apoptosis Protein 2 (IAP 2) as a regulator of innate immune signaling in Drosophila.

"Innate immunity in vertebrates and invertebrates is of central importance as a biological programme for host defense against pathogenic challenges. To find novel components of the Drosophila immune deficiency (IMD) pathway in cultured hemocyte-like cells, we screened an RNA interference library for modifiers of a pathway-specific reporter," wrote V. Gesellchen and colleagues, German Cancer Research Center.

"Selected modifiers were further characterized using an independent reporter...

Want to see the full article?

Purchase this article for only $3.00

We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.

Welcome to NewsRx!

Learn more about a six-week, no-risk free trial of Gene Therapy Weekly

Source: Gene Therapy Weekly (2006-03-02)

NewsRx is Social

Top Medical Newsletters

Awards

Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005

Facts & Stats

NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.

Google 2010 PageRank: #2 Among Top Health News and Media Publications
Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry