Published in Gene Therapy Weekly, March 2nd, 2006
"Innate immunity in vertebrates and invertebrates is of central importance as a biological programme for host defense against pathogenic challenges. To find novel components of the Drosophila immune deficiency (IMD) pathway in cultured hemocyte-like cells, we screened an RNA interference library for modifiers of a pathway-specific reporter," wrote V. Gesellchen and colleagues, German Cancer Research Center.
"Selected modifiers were further characterized using an independent reporter...
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