Virology
Liver viral-mediated transduction is primarily restricted by capsid serotype
Published in Gene Therapy Weekly, March 30th, 2006
"We and others have recently reported highly efficient liver gene transfer with AAV-8 pseudotypes, i.e., AAV-2 genomes packaged into AAV-8 capsids. Here we studied whether liver transduction could be further enhanced by using viral DNA packaging sequences (inverted terminal repeats [ITRs]) derived from AAV genotypes other than 2," wrote D. Grimm and colleagues, Stanford University. "To this end, we generated two sets of vector constructs carrying expression cassettes embedding a gfp gene or...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Gene Therapy Weekly
Source: Gene Therapy Weekly (2006-03-30)
More Articles from Gene Therapy Weekly
- Antisense Technology
Antisense technology can reduce tamoxifen-induced CYP3A2 expression and DNA adducts - Cardiology
Cardiac dysfunction is associated with depression of proteasome activities - DNA Research
Tetrahydrobiopterin supplementation improves vascular dysfunction in insulin-resistance - Virology
Small interfering RNA inhibits Anatid Herpes Virus-1 replication - Adenocarcinomas
Fibroblast growth factor has oncogenic activity in ovarian endometrioid adenocarcinomas - Adenoviruses
An oncolytic adenovirus demonstrates greater efficacy without increased toxicity - More from this issue of Gene Therapy Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
