Genetics & Genomics
Stem cell gene downregulation associated with differentiation of male germ cell tumors
Published in Gene Therapy Weekly, March 30th, 2006
"Adult mate germ cell tumors (GCTs) comprise distinct groups: seminomas and nonseminomas, which include pluripotent embryonal carcinomas as well as other histologic subtypes exhibiting various stages of differentiation. Almost all GCTs show 12p gain, but the target genes have not been clearly defined," scientists writing in the journal Cancer Research report.
According to J.E. Korkola and colleagues at Memorial Sloan-Kettering Cancer Center in New York, "To identify 12p target genes, we examined Affymetrix (Santa Clara, CA) U133A+B microarray...
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Source: Gene Therapy Weekly (2006-03-30)
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