Susan Hasty, Publisher
Table of Contents . . . April 13th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Liposome Delivery - Cationic liposome decoy complex suppresses tumor necrosis factor alpha
Neuroscience - Basic FGF expression in astrocytes affects dopamine neuron synaptic function and development
Ovarian Cancer - Effective ovarian cancer treatment strategies target Raf-1 mRNA
Prostate Cancer - Prostate cancers are effectively treated using oncolytic herpes simplex virus
RNA Interference - RNA interference allows transgenic screening
Allergy & Immunology - Autoantibodies to diacyl-phosphatidylethanolamine recognize cytoplasmic domains
Allergy & Immunology - T cell activation is increased in the absence of the autoimmune regulator
Antisense Technology - Antisense oligonucleotide library validates Eg5 as a drug development target
Apoptosis - An adenovirus mutant induces apoptosis and cell-cycle arrest in tumor cells
Apoptosis - Schisandrin B enhanced doxorubicin-induced apoptosis of cancer cells
Arthritis - Inflammatory bone destruction requires p38 MAPK activation
Breast Cancer - Breast cancer therapy utilizes retrovirus-mediated tk gene
Breast Cancer - Possible breast cancer therapy believed to be inhibition of Notch signaling
Business & Finance - Enzo Biochem reports second quarter results, HIV-1 Stealth Vector trial initiated
COX-2 - Cyclooxygenase-2 pre-mRNA targeted using antisense morpholino oligonucleotides
Cancer Gene Therapy - Bladder cancer growth is inhibited by an adenovirus expressing dual therapeutic genes
Cancer Gene Therapy - Cervical cancer cell death can be induced by E6 siRNA
Cancer Gene Therapy - Enhanced bladder cancer gene therapy involves restoration of viral receptor expression
Cancer Gene Therapy - New research in the area of cancer gene therapy detailed
Cancer Gene Therapy - Ovarian cancer metastasis is inhibited by adeno-associated virus-mediated gene transfer
Cancer Gene Therapy - Prostate cancer radiation therapy is aided by the use of gene therapy
Cancer Gene Therapy - Recent findings in cancer gene therapy described
Cancer Gene Therapy - Recent findings in cancer gene therapy provide new insights
Cancer Gene Therapy - Small interfering RNA-mediated depletion of CD44 v5 reduced tumor cell invasion
Cancer Gene Therapy - Tumor angiogenesis is suppressed by oncolytic replication-competent adenovirus
Cancer Therapy - Chemotherapy can be enhanced by molecular targeting of BCL2 and BCLXL proteins
Cancer Therapy - Prostate cancer cell superoxide production and apoptosis is enhanced by p53
Cancer Therapy - Recent findings in cancer therapy described
Cancer Therapy - Targeted tumor therapy is achieved using an antisense compound
Cardiology - Estrogen receptor alpha mediates potassium channel stimulation
Cardiology - GDF15/MIC-1 functions as a protective and antihypertrophic factor
Cardiology - Progressive myocardial ischemia stalls upon angiogenic induction by VEGF-C
Cell Differentiation - Skeletal muscle satellite cell differentiation requires lamin A/C and emerin
Chemotherapy - Inex licenses three targeted chemotherapy products to Hana Biosciences
Cholangiocarcinoma - Cholangiocarcinoma is treatable with combination virus-radiation therapy
Colon Cancer - Colon cancer targeting of parvoviruses is achieved by insertion in P4 promoter
Colorectal Cancer - Chemotherapy-induced colorectal cancer cell death inhibited by c-FLIP
DNA Research - Pausing during reverse transcription increases the rate of retroviral recombination
DNA Research - Smad3 regulates telomerase reverse transcriptase via growth factor beta
DNA Research - Two-step red-mediated recombination allows DNA manipulation in Escherichia coli
DNA Vaccine - DNA vaccine encoding Der p2 allergen down-regulates STAT6 expression
Developmental Biology - Gene expression of Cox5a, 5b, or 6b1 functions in preimplantation mouse embryos
Developmental Biology - Xenopus hypaxial myogenesis involves lbx1
Diet & Nutrition - Ghrelin neutralization ameliorates obesity in diet-induced obese mice
Drug Delivery - Cationic liposomes are promising in drug and gene delivery
Drug Delivery - Endosomes and lysosomes are the receptors for peptide localization
Drug Development - ALS Association funds study in monkeys of drug with potential to treat Lou Gehrig disease
Drug Development - Corroles are specifically delivered to tumor cells via noncovalent conjugates
Drug Development - Intravenous delivery of plasmid DNA generates antibody
Embryogenesis - Foxd3 mediates zebrafish myf5 expression during early somitogenesis
Embryogenesis - Nodal gene expression and signaling is cooperatively and autonomously regulated in Xenopus
Endocrinology - Growth hormone determines sexual dimorphism of hepatic cytochrome expression
Endometrial Cancer - Endometrial carcinoma chemoresistance involves placental leucine aminopeptidase
Endometrial Cancer - Neonatal estrogenic exposure suppresses PTEN-related endometrial carcinogenesis
Gastric Cancer - Disseminated peritoneal scirrhous gastric cancer is responsive to gene-drug therapy
Gene Research - Cancer pathogenesis involves small noncoding microRNA
Gene Therapy - Cationic gene delivery polymer has been synthesized and characterized
Gene Therapy - Uronic acid functionalized copolymers can be synthetic gene carriers
Gene Therapy - Viral vectors activate endothelial cell signal transduction
Gene Transfer - LYVE-1 cDNA delivery creates blocking antibodies
Genetic Research - Compendia Bioscience obtains exclusive rights to commercialize Oncomine
Genetics & Genomics - Mycobacterial vaccination and infection induces transcriptional responses
Genetics & Genomics - Study results on ChondroGene's blood-based molecular diagnostics tests published in paper
Hematology - Neutrophil chemotaxis requires Hem-1 complexes
Hepatocellular Carcinoma - HCC tumorigenicity is reduced by knock-down of hepatitis B virus X protein
Herpes Simplex Virus - Treatment of intravaginal HSV-2 infection is aided by mucosal innate activation
Human Papillomavirus - Human papillomavirus-associated oropharyngeal cancers with favorable prognosis identified
Human Papillomavirus - Human papillomaviruses are genotyped by bead-based multiplex method
Imaging - Positron emission tomography targets oncolytic virus in prostate cancer therapy
Immunotherapy - Heat labile Escherichia coli enterotoxin is potential adjuvant for transcutaneous cancer immunotherapy
Leukemia - Adult T cell leukemia treated by curcumin
Leukemia - Myeloid leukemia cell differentiation involves a novel signaling molecule
Leukemia - Pre-B lymphoblastic leukemia cell aberrant splicing is induced by BCR-ABL1
Liposome Delivery - Liposome-DNA complexes inhibit tumor angiogenesis and elicit antitumor activity
Lymphoma - Studies describe new findings in lymphoma research
Melanoma - Melanoma is regressed in a murine model by RLIP76 depletion
Melanoma - Melanosomal targeting sequences target epitope presentation and mobilization
Multiple Sclerosis - Oligodendrocyte glycoprotein antibodies are diagnostic of early inflammation in multiple sclerosis
Neuroscience - Extracellular matrix-degrading proteases affect spatial learning and synaptic plasticity
Neuroscience - Neuroticism mediates serotonin transporter gene association with lifetime major depression
Neuroscience - Neurotoxicity is attenuated by adenoviral gene transfer of superoxide dismutase
Parkinson Disease - Research add new data to Parkinson disease body of knowledge
Personnel - Michael Shoup named SurModic's VP of quality, regulatory and clinical affairs
Personnel - Vesta Therapeutics names four researchers to newly formed scientific advisory board
Physiology - Intermedin activates aortic L-Arg/nitric oxide synthase/nitric oxide pathway
Physiology - Novel targets identified in a phosphatidylinositol 3-kinase-independent pathway
Physiology - RNA interference-based screen identifies MAP4K4/NIK as a negative regulator
Prostate Cancer - Prostate cancer epithelial cell channels display differential roles
Proteomics - Macrophage cholesterol homeostasis and inflammation involves adipocyte enhancer-binding protein 1
Stem Cell Research - Genetically corrected Fanconi anemia bone marrow cells can repopulate
Stem Cell Research - Stem cell-derived dendritic cells induce immunity against metastatic melanoma
Vector Development - Findings in vector development provide new insights
Vector Development - Recent findings in vector development provide new insights
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