Susan Hasty, Publisher
Table of Contents . . . April 20th, 2006
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Gene Therapy Weekly | Other Publications
Cancer Gene Therapy - Isoform-specific silencing defines Livin beta as key mediator of apoptosis inhibition
Gene Silencing - Imprinting control region affects the expression of Gnas cluster transcripts
Genetics & Genomics - MUC5AC gene expression in human lung epithelial cells is medicated by dexamethasone
Vector Development - Human peritoneal mesothelial cell growth factor expression is inhibited by shRNA
Adverse Drug Reaction - Adverse effects are associated with bone morphogenetic protein-2 use
Allergy & Immunology - An immunoadjuvant chaperone induces signals upon dendritic cell interaction
Analgesia - Na+ channel analgesics compared in rat sensory neurons and Nav1.2 channels
Apoptosis - Co-expression of metallothionein and p53 implicated in tumor cell apoptosis
Apoptosis - Neuronal apoptosis involves Bid cleavage and translocation to mitochondria
Apoptosis - Researchers' work adds to apoptosis body of knowledge
Apoptosis - p73 overexpression enhanced cisplatin-induced apoptosis in HeLa cells
Bladder Cancer - Bladder cancer cells are chemosensitized by antisense oligodeoxynucleotides and siRNA
Business & Finance - Corautus Genetics reports 2005 financials, updates on temporary suspension of GENASIS trial
Business Update - CytoGenix enters into a supply agreement with GE Healthcare for DNA production reagents
Cancer Gene Therapy - Adenoviral transduction of canine osteosarcoma cells enhances infectivity
Cancer Gene Therapy - Adenovirus-mediated antisense expression inhibits colorectal cancer cell growth
Cancer Gene Therapy - Combination antisense oligodeoxyribonucleotide-radiation therapy evaluated
Cancer Gene Therapy - Laryngeal tumor growth is inhibited by knockdown of Stat3 expression using RNAi
Cancer Gene Therapy - Lung cancer therapy is achieved by an adenovirus vector system
Cancer Gene Therapy - Oncolytic HSV-1 vectors armed with immunostimulatory genes enhances antitumor efficacy
Cancer Therapy - Celecoxib leads to G2 /M arrest
Cancer Therapy - Effective cancer therapy is achieved with an alpha-particle emitter
Cancer Vaccine - Allogeneic tumor cells expressing fusogenic membrane glycoproteins enable cancer immunotherapy
Cardiology - Cardiomyocyte hypertrophy is exacerbated by selective loss of fine tuning Gq/11 signaling
Cardiology - Recombinant factor XIII reduces severe pleural effusion after open-heart surgery
Chlamydia Vaccine - Chlamydia pneumoniae infection is prevented by IgA and T cell mucosal immune defenses
Clinical Trials - First patients complete infusions in phase II clinical trial for HIV/AIDS gene-based immunotherapy
Crohn Disease - Crohn disease lamina propria lymphocytes utilize Flip to resist FAS-mediated apoptosis
Cystic Fibrosis - Researchers' work adds to cystic fibrosis body of knowledge
Cytotoxicity - Differential cytotoxicity expression is influenced by D-ring hydrogen bond donor
DNA Immunization - Naked DNA immunization targeting survivin induces humoral and cellular immune responses
DNA Research - DNA strand breaks induce CAF-1 expression in quiescent human cells
DNA Research - Epigenetic gene silencing reverts cholesterol auxotrophy of NS0 cells
DNA Research - Sanguinarine and chelerythrine alter hepatoma cell CYP1A1 expression and activity
DNA Vaccine - Brucella abortus DNA vaccine was evaluated by expression antigen fusion
DNA Vaccine - Clonorchis sinensis fatty acid-binding protein induces an immune response
DNA Vaccine - Mycobacterium tuberculosis protection is conferred by DNA vaccine
DNA Vaccine - DNA vaccine humoral immune response are dissected
DNA Vaccine - Vaccination of mice with DNA vaccine induces Trichinella spiralis immune response
Dendritic Cells - Dendritic cell association with natural killer cells is affected by DNAM-1 ligands
Developmental Biology - B-lineage precursors in bone marrow stimulated by a hybrid cytokine
Developmental Biology - Mesenchymal epimorphin is important for pancreatic duct morphogenesis
Diabetes Research - Gene technology increases pancreatic islet cell survivability in animal study
Elastic Fibers - Fibulin-4 disruption abolishes elastogenesis and causes perinatal lethality
Endometrial Cancer - Endometrial cancer cell proliferation is mediated by G protein-coupled receptor
Factor VIII - Tolerance to factor VIII occurs following an Arg593 to Cys substitution
Gene Research - Triple helix-forming oligonucleotides mediate targeted cross-linking of the human beta-globin gene
Genetics & Genomics - Circadian oscillation of clock gene expression is repressed by prednisolone
HIV/AIDS Therapy - Failure of HIV-exposed T cells to activate dendritic cells is reversible
Hematology - von Willebrand factor-mediated platelet thrombi size is regulated by ADAMTS13
Hepatitis C Virus - Data advance knowledge in hepatitis C virus research
Hepatitis C Virus - Hepatitis C envelope 2 protein inhibits signaling for T-lymphocyte migration
Hepatocellular Cancer - Fas-associated phosphatase-1 proposed as tumor suppressor gene in hepatocellular carcinoma
Hyperalgesia - Changes in pain behavior and histology are caused by tumor necrosis factor-alpha
Imaging - Membrane antibody receptor allows noninvasive imaging of gene expression
Immunotherapy - An oligodeoxynucleotide mucosal adjuvant may prevent upper respiratory infections
Immunotherapy - Small-interfering RNAs are efficiently delivered via reconstituted influenza virus envelopes
Infectious Diseases - Chlamydophila pneumoniae-mediated GM-CSF release in bronchial epithelial cells defined
Keratitis - Herpetic stromal keratitis is suppressed by immunomodulation
Leukemia - Chronic lymphocytic leukemia cell survival is promoted by high Mda-7 expression
Lipoproteins - High-density lipoprotein structure is disrupted by serum opacity factor
Lipoproteins - LDL receptor deficiency or apoE mutations induce hypertriglyceridemia in mice
Lung Cancer - Induction of apoptosis in lung cancer cells by all-trans retinoic acid studied
Measles-Mumps-Rubella Vaccine - Measles-mumps-rubella vaccine response is aided by leukocyte antigen haplotypes
Melioidosis Vaccine - Anti-Burkholderia pseudomallei activity is produced using flagellin
Nephrology - Decoy oligonucleotides suppress kidney extracellular matrix gene expression and fibrosis
Nephrotoxicity - Gentamicin-induced nephrotoxicity is alleviated by inflammation and apoptosis inhibition
Neuroscience - Circadian transcription factor DBP functions in hippocampal plasticity
Neuroscience - Human neural progenitors deliver glial cell line-derived neurotrophic factor
Orthopedics - Orthopedic researchers discuss role of gene therapy and stem cells at conference
Pancreatic Cancer - Pancreatic cancer RELN pathway disruption identified
Patents - U.S. patent granted for intellectual property around use of microbeads
Physiology - Multiple signalling pathways are involved in skeletal muscle cell glucose uptake
Physiology - Oxidative metabolism of linoleic acid modulates PPAR-beta/delta suppression of PPAR-gamma activity
Progenitor Cells - AKT induces erythroid-cell maturation of fetal liver progenitor cells
Proteomics - New findings in proteomics described
Proteomics - Prostacyclin receptor loop mediates interaction with G alpha s protein
Rabies Vaccine - Rabies DNA vaccine induces long-lasting neutralizing antibodies and protection
Retinoic Receptors - Retinoid X receptor ligand binding dynamics clarified
SARS Vaccine - Anti-SARS-CoV immunity is induced by a novel CpG oligodeoxynucleotide
Sendai Virus - T cell epitopes of Sendai virus are not solely responsible for viral clearance
Stem Cell Research - Adult neural stem cell self-renewal suppressed by p53
Stem Cell Research - Hematopoietic stem cells modeled for autologous transplantation
Tumorigenesis - How to decrease p27(Kip1) levels during tumor development discussed
Vector Development - Recent findings in vector development described
Wound Healing - Gene therapy stimulates angiogenesis in healing wounds
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