Cancer Therapy
Effective cancer therapy is achieved with an alpha-particle emitter
Published in Gene Therapy Weekly, April 20th, 2006
"The NIS gene is currently explored in several trials to eradicate experimental cancer with radiodine (I-131) by its beta-emission. We recently characterized NIS-specific cellular uptake of an alternative halide, radioastatine (At-211), which emits high-energy alpha-particles.
"The aim of this study was to investigate in vivo effects of the high linear energy transfer (LET) emitter At-211 on tumor growth and outcome in nude mice,"...
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Source: Gene Therapy Weekly (2006-04-20)
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